Evidence map›Paper›PMID 28277925›Full record

ReviewFly2017

Methods to investigate the structure and connectivity of the nervous system.

Donghyung Lee, Ting-Hao Huang, Aubrie De La Cruz, Antuca Callejas, Carlos Lois

Abstract readReview
In one paragraph

Review in Fly, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. A connectome of theeLife · 2021
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Donghyung Leea Division of Biology and Biological Engineering , California Institute of Technology , Pasadena , CA , USA.
Ting-Hao Huanga Division of Biology and Biological Engineering , California Institute of Technology , Pasadena , CA , USA.
Aubrie De La Cruza Division of Biology and Biological Engineering , California Institute of Technology , Pasadena , CA , USA.
Antuca Callejasa Division of Biology and Biological Engineering , California Institute of Technology , Pasadena , CA , USA.
Carlos Loisa Division of Biology and Biological Engineering , California Institute of Technology , Pasadena , CA , USA.

Funding

Tracing Brain Circuits by Transneuronal Control of TranscriptionU01MH109147 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HONG, ELIZABETH JENNIFER, LOIS, CARLOS · 2015 to 2017
$3.1M
NIMH NIH HHS U01 MH109147
6 · The paper itself

Abstract

Understanding the computations that take place in neural circuits requires identifying how neurons in those circuits are connected to one another. In addition, recent research indicates that aberrant neuronal wiring may be the cause of several neurodevelopmental disorders, further emphasizing the importance of identifying the wiring diagrams of brain circuits. To address this issue, several new approaches have been recently developed. In this review, we describe several methods that are currently available to investigate the structure and connectivity of the brain, and discuss their strengths and limitations.

Indexed as

AnimalsBrainDrosophilaGene Expression ProfilingMicroscopy, ElectronNerve NetNeuronsbrain circuitconnectomicsneuronsynapsewiring diagram

Identifiers

PMID28277925
PMCPMC5552278

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.