ArticleJournal of clinical laboratory analysis2018
Association between sickle cell anemia and alpha thalassemia reveals a high prevalence of the α
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Thalassemia in Sub-Saharan Africa: epidemiology, diagnosis, and management - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Prevalence and genetic analysis of triplicated α-globin gene in Ganzhou region using high-throughput sequencing.Frontiers in genetics · 2023Article
- Global Globin Network Consensus Paper: Classification and Stratified Roadmaps for Improved Thalassaemia Care and Prevention in 32 Countries.Journal of personalized medicine · 2022Article
- Association of alpha-thalassemia and Glucose-6-Phosphate Dehydrogenase deficiency with transcranial Doppler ultrasonography in Nigerian children with sickle cell anemia.Journal of clinical laboratory analysis · 2021Article
- Co-Inheritance of alpha-thalassemia and sickle cell disease in a cohort of Angolan pediatric patients.Molecular biology reports · 2020Article
- Influence of alpha thalassemia on clinical and laboratory parameters among nigerian children with sickle cell anemia.Journal of clinical laboratory analysis · 2019Article
- Homozygous Deletion Alpha-Thalassemia and Hereditary Persistence of Fetal Hemoglobin, Two Genetic Factors Predictive the Reduction of Morbidity and Mortality During Pregnancy in Sickle Cell Patients. A Report from the Democratic Republic of Congo.Mediterranean journal of hematology and infectious diseases · 2019Article
- Association between sickle cell anemia and alpha thalassemia reveals a high prevalence of the αJournal of clinical laboratory analysis · 2018Article
- Dental tissues of sickle cell anemia and its impact on the quality of life related to oral health.Hematology, transfusion and cell therapyArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInformation about the association with alpha thalassemia in sickle cell patients is unknown in the Democratic Republic of Congo. There is very little data on the alpha thalassemia in patients suffering from sickle cell anemia in Central Africa, and their consequences on the clinical expression of the disease.
methodsA cross-sectional study was conducted in 106 sickle cell patients living in the country's capital Kinshasa. The diagnosis of sickle cell anemia was confirmed with a molecular test using PCR-RFLP (restriction fragment length polymorphism) technique. The diagnosis of thalassemia was performed by the technique of multiplex ligation dependent probe amplification.
resultsThe mean age of our patients was 22.4±13.6 years. The α
conclusionThe prevalence of α
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.