Evidence map›Paper›PMID 28276545›Full record

ArticleLab on a chip2017

Isolation and concentration of bacteria from blood using microfluidic membraneless dialysis and dielectrophoresis.

L D'Amico, N J Ajami, J A Adachi, P R C Gascoyne, J F Petrosino

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
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  6. Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

L D'AmicoAlkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA. jpetrosi@bcm.edu and Advanced Electrofluidic Systems, LLC, Houston, Texas, USA.ORCID 0000-0001-9839-7568
N J AjamiAlkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA. jpetrosi@bcm.edu.
J A AdachiDepartment of Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
P R C GascoyneDepartment of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA and Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA and Advanced Electrofluidic Systems, LLC, Houston, Texas, USA.
J F PetrosinoAlkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA. jpetrosi@bcm.edu.
Baylor College of Medicine · USThe University of Texas MD Anderson Cancer Center · US

Funding

Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
NIBIB NIH HHS T32 EB007507
6 · The paper itself

Abstract

A microfluidic system that combines membraneless microfluidic dialysis and dielectrophoresis to achieve label-free isolation and concentration of bacteria from whole blood is presented. Target bacteria and undesired blood cells are discriminated on the basis of their differential susceptibility to permeabilizing agents that alter the dielectrophoretic behavior of blood cells but not bacteria. The combined membraneless microdialysis and dielectrophoresis system isolated 79 ± 3% of Escherichia coli and 78 ± 2% of Staphylococcus aureus spiked into whole blood at a processing rate of 0.6 mL h

Indexed as

BacteremiaBacteriaBacterial LoadComputer SimulationDNA, BacterialElectrophoresisEquipment DesignHumansMicrofluidic Analytical TechniquesRNA, Ribosomal, 16SDNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID28276545
PMCPMC5894507
OpenAlexW2594335223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.