Evidence map›Paper›PMID 28276525›Full record

ArticleScientific reports2017

Regulation of molecular clock oscillations and phagocytic activity via muscarinic Ca

Rina Ikarashi, Honami Akechi, Yuzuki Kanda, Alsawaf Ahmad, Kouhei Takeuchi, Eri Morioka, Takashi Sugiyama, Takashi Ebisawa, Masaaki Ikeda, Masayuki Ikeda

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Spatial organization of lysosomal exocytosis relies on membrane tension gradients.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Circadian Regulation of Retinal Pigment Epithelium Function.International journal of molecular sciences · 2022
    Review
  5. Biochemistry and physiology of zebrafish photoreceptors.Pflugers Archiv : European journal of physiology · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. The MScientific reports · 2019
    Article
  11. Ocular Clocks: Adapting Mechanisms for Eye Functions and Health.Investigative ophthalmology & visual science · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rina IkarashiGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Honami AkechiGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Yuzuki KandaGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Alsawaf AhmadGraduate School of Innovative Life Science, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Kouhei TakeuchiGraduate School of Innovative Life Science, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Eri MoriokaGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
Takashi SugiyamaAdvanced Core Technology Department, Research and Development Division, Olympus Co. Ltd., 2-3 Kuboyama, Hachioji, Tokyo 192-8512, Japan.
Takashi EbisawaDepartment of Psychiatry, Tokyo Metropolitan Police Hospital, 4-22-1 Nakano, Nakano-ku, Tokyo 164-8541, Japan.
Masaaki IkedaDepartment of Physiology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.
Masayuki IkedaGraduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama city, Toyama 930-8555, Japan.
University of Toyama · JPSaitama Medical University · JPOlympus (Japan) · JPTokyo Metropolitan Police Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vertebrate eyes are known to contain circadian clocks, however, the intracellular mechanisms regulating the retinal clockwork remain largely unknown. To address this, we generated a cell line (hRPE-YC) from human retinal pigmental epithelium, which stably co-expressed reporters for molecular clock oscillations (Bmal1-luciferase) and intracellular Ca

Indexed as

Biological ClocksCalciumCalcium SignalingCell Line, TransformedGene Expression RegulationHumansPhagocytosisReceptor, Muscarinic M3Retinal Pigment EpitheliumCalciumReceptor, Muscarinic M3

Identifiers

PMID28276525
PMCPMC5343479
OpenAlexW2593138384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.