Evidence map›Paper›PMID 28276487›Full record

Trial reportScientific reports2017

Behavioral responses to noxious stimuli shape the perception of pain.

Elisabeth S May, Laura Tiemann, Paul Schmidt, Moritz M Nickel, Nina Wiedemann, Christian Dresel, Christian Sorg, Markus Ploner

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisabeth S MayDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Laura TiemannDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Paul SchmidtDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Moritz M NickelDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Nina WiedemannDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Christian DreselCenter for Neuroscience, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA.
Christian SorgDepartments of Neuroradiology and Psychiatry and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.
Markus PlonerDepartment of Neurology and TUM-Neuroimaging Center, Technische Universität München, 81675 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain serves vital protective functions. To fulfill these functions, a noxious stimulus might induce a percept which, in turn, induces a behavioral response. Here, we investigated an alternative view in which behavioral responses do not exclusively depend on but themselves shape perception. We tested this hypothesis in an experiment in which healthy human subjects performed a reaction time task and provided perceptual ratings of noxious and tactile stimuli. A multi-level moderated mediation analysis revealed that behavioral responses are significantly involved in the translation of a stimulus into perception. This involvement was significantly stronger for noxious than for tactile stimuli. These findings show that the influence of behavioral responses on perception is particularly strong for pain which likely reflects the utmost relevance of behavioral responses to protect the body. These observations parallel recent concepts of emotions and entail implications for the understanding and treatment of pain.

Indexed as

Pain PerceptionTouchAdultFemaleHumansMalePain

Identifiers

PMID28276487
PMCPMC5343499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.