ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2017
Increasing survival gap between young and elderly gastric cancer patients.
Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS).Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022Trial
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- Gastro-Esophageal Disorders of the Geriatric Population.The American journal of gastroenterology · 2025Article
- Nomogram models for predicting lymph node metastasis and prognosis in early gastric cancer 60 or older: a population-based cohort study.Discover oncology · 2025Article
- Predictive Factors Aiding in the Estimation of Intraoperative Resources in Gastric Cancer Oncologic Surgery.Cancers · 2025Article
- Combining nutritional status with TNM stage: a physiological update on gastric cancer staging for improving prognostic accuracy in elderly patients.International journal of clinical oncology · 2022Article
- Increasing disparities in the proportions of active treatment and 5-year overall survival over time by age groups among older patients with gastric cancer in Korea.Frontiers in public health · 2022Article
- Development and Validation of an Age-Related Gastric Cancer-Specific Immune Index.Journal of inflammation research · 2022Article
- ARE THERE DIFFERENCES IN LAPAROSCOPIC GASTRECTOMY MORBIDITY AND MORTALITY BETWEEN YOUNG AND OLDER?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Observational
- Survival analysis of stage II gastric cancer patients after D2 gastrectomy: a Chinese people-based research.BMC gastroenterology · 2021Article
- Prognostic performance of different lymph node classification systems in young gastric cancer.Journal of gastrointestinal oncology · 2021Article
- Article
- Preoperative Prognostic Nutrition Index as a Prognostic Indicator of Survival in Elderly Patients Undergoing Gastric Cancer Surgery.Cancer management and research · 2021Article
- Prognostic Nomograms for Nonelderly Adults with Gastric Signet Ring Cell Carcinoma.BioMed research international · 2021Article
- Mortality calculator as a possible prognostic predictor of overall survival after gastrectomy in elderly patients with gastric cancer.World journal of surgical oncology · 2020Article
- Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictors of tumor response in hepatocellular carcinoma after DEB-TACE.European radiology · 2020Article
- A nomogram for predicting cancer-specific survival in different age groups for operable gastric cancer: a population-based study.Translational cancer research · 2020Article
- Diffuse Reduction of Spleen Density Is an Independent Predictor of Post-Operative Outcomes After Curative Gastrectomy in Gastric Cancer: A Multi-Center Study.Frontiers in oncology · 2020Article
- More attention should be paid to adult gastric cancer patients younger than 35 years old: extremely poor prognosis was found.Journal of Cancer · 2019Article
- Higher Risk of Lymph Node Metastasis in Young Patients with Early Gastric Cancer.Journal of Cancer · 2019Article
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5 authors.
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Abstract
introductionThis study investigates the treatment and survival of young versus elderly potentially curable gastric cancer patients in the Netherlands. PATIENTS AND
methodsAll noncardia gastric cancer patients with potentially curable gastric cancer according to stage (cTx-3, cNx-3, and cMx-0) diagnosed between 1989 and 2013 were selected from the Netherlands Cancer Registry. Trends in treatment and overall survival were compared between young patients (younger than 70 years) and elderly patients (70 years or older). Multivariable logistic regression analysis was used to examine the probability of patients undergoing surgery and chemotherapy in the most recent period. Multivariable Cox regression analysis was used to identify independent factors associated with survival.
resultsIn total, 8107 young and 13,814 elderly gastric cancer patients were included. There was a major increase in the proportion of patients treated with resection and chemotherapy after 2004-2008. In young patients the increase was from 2.6% in 1999-2003 to 63% in 2009-2013 (p < 0.01). Also an increase was noticed among elderly patients, from 0.1% to 16% (p < 0.01). Median survival increased from 2004 to 2008 onward particularly in young patients and to a lesser extent in elderly patients (from 28 to 41 months vs from 11 to 13 months). Multivariable Cox regression analyses confirmed that overall survival improved for young and elderly patients. DISCUSSION: Young patients experienced a stronger improvement in survival than elderly patients, resulting in an increasing survival gap. The literature shows this is a problem not only in the Netherlands but also throughout Europe. The dissimilarity in treatment between young and elderly patients could be the reason for this difference.
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