Evidence map›Paper›PMID 28275687›Full record

ReviewCellular and molecular gastroenterology and hepatology2017

Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions.

Juanita L Merchant, Lin Ding

Open access · goldAbstract readReview
In one paragraph

Review in Cellular and molecular gastroenterology and hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Myeloid-derived suppressor cells modulation in the context of tumor microenvironment for gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8Laboratory investigation; a journal of technical methods and pathology · 2022
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Juanita L MerchantDepartment of Internal Medicine-Gastroenterology, University of Michigan, Ann Arbor, Michigan; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
Lin DingDepartment of Internal Medicine-Gastroenterology, University of Michigan, Ann Arbor, Michigan.
University of Michigan–Ann Arbor · US

Funding

University of Michigan Center for Gastrointestinal ResearchP30DK034933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OWYANG, CHUNG · 1986 to 2021
$22.5M
Role of Hedgehog Signaling in Chronic Gastritis and MetaplasiaP01DK062041 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MERCHANT, JUANITA L. · 2002 to 2017
$20.6M
NIDDK NIH HHS P01 DK062041NIDDK NIH HHS P30 DK034933
6 · The paper itself

Abstract

Since its initial discovery in

Indexed as

ATPase, adenosine triphosphataseDAMP, damage-associated molecular patternDAMPsGLI1GLI, glioma-associated proteinGr-MDSC, granulocytic myeloid-derived suppressor cellHH, hedgehogHHIP, hedgehog-interacting proteinIFN, interferonIL, interleukinMDSC, myeloid-derived suppressor cellMDSCsMetaplasiaMo-MDSC, monocytic myeloid-derived suppressor cellmRNA, messenger RNAPTCH, PatchedSHHSHH, sonic hedgehogSLFN4, Schlafen 4SMO, SmoothenedSPEMSPEM, spasmolytic polypeptide–expressing mucosaSP, spasmolytic polypeptideSST, somatostatinTLR, Toll-like receptor

Identifiers

PMID28275687
PMCPMC5331830
OpenAlexW2575610047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.