Evidence map›Paper›PMID 28275595›Full record

ArticleOcular oncology and pathology2017

Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): A Case Report.

Lauren E Hudson, Pia R Mendoza, Jiong Yan, Hans E Grossniklaus

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Ocular oncology and pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lauren E HudsonDepartment of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA.
Pia R MendozaDepartment of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA; L.F. Montgomery Ophthalmic Pathology Laboratory, Department of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Ga., USA.
Jiong YanDepartment of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA.
Hans E GrossniklausDepartment of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA; L.F. Montgomery Ophthalmic Pathology Laboratory, Department of Ophthalmology, BT 428 Emory Eye Center, Atlanta, Ga., USA; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Ga., USA.
Emory University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

purposeTo report the clinical and histopathological findings of a reactive retinal astrocytic tumor (RRAT) that progressed to massive retinal gliosis. OBSERVATIONS: The patient presented with an elevated, white-yellow retinal mass and extensive retinal exudation in the left eye. Progressive enlargement of the mass and proliferative vitreoretinopathy eventually led to phthisis bulbi and enucleation. Histologically, the mass showed a predominant astrocytic component with intense glial fibrillary acidic protein staining, hyperplasia, fibrous metaplasia, and osseous metaplasia of the retinal pigment epithelium. The Ki-67 proliferative index was <5%, and few scattered vascular channels were observed. CONCLUSIONS AND IMPORTANCE: These findings show that this tumor is the result of a reactive glial process rather than of neoplastic vascular proliferation. Massive retinal gliosis probably represents the advanced stage of RRAT.

Indexed as

Focal nodular gliosisMassive retinal gliosisProliferative vitreoretinopathyReactive retinal astrocytic tumorVasoproliferative tumor

Identifiers

PMID28275595
PMCPMC5318941
OpenAlexW2515267093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.