Evidence map›Paper›PMID 28275584›Full record

ArticleFrontiers in cellular and infection microbiology2017

Vitamin C Pretreatment Enhances the Antibacterial Effect of Cold Atmospheric Plasma.

Saga Helgadóttir, Santosh Pandit, Venkata R S S Mokkapati, Fredrik Westerlund, Peter Apell, Ivan Mijakovic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Polymyxin B complexation enhances the antimicrobial potential of graphene oxide.Frontiers in cellular and infection microbiology · 2023
    Article
  4. Control Measurements ofFoods (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Non-thermal plasma causesFrontiers in cellular and infection microbiology · 2022
    Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
  14. Medically important biofilms and non-thermal plasma.World journal of microbiology & biotechnology · 2018
    Review
  15. Green synthesis of gold and silver nanoparticles fromInternational journal of nanomedicine · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Saga HelgadóttirDepartment of Physics, Chalmers University of Technology Göteborg, Sweden.
Santosh PanditSystems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology Gothenburg, Sweden.
Venkata R S S MokkapatiSystems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology Gothenburg, Sweden.
Fredrik WesterlundChemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology Gothenburg, Sweden.
Peter ApellDepartment of Physics, Chalmers University of Technology Göteborg, Sweden.
Ivan MijakovicSystems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of TechnologyGothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Technical University of DenmarkLyngby, Denmark.
Chalmers University of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial biofilms are three-dimensional structures containing bacterial cells enveloped in a protective polymeric matrix, which renders them highly resistant to antibiotics and the human immune system. Therefore, the capacity to make biofilms is considered as a major virulence factor for pathogenic bacteria. Cold Atmospheric Plasma (CAP) is known to be quite efficient in eradicating planktonic bacteria, but its effectiveness against biofilms has not been thoroughly investigated. The goal of this study was to evaluate the effect of exposure of CAP against mature biofilm for different time intervals and to evaluate the effect of combined treatment with vitamin C. We demonstrate that CAP is not very effective against 48 h mature bacterial biofilms of several common opportunistic pathogens:

Indexed as

Anti-Bacterial AgentsAscorbic AcidAtmospheric PressureBiofilmsEscherichia coliMicrobial ViabilityPlasma GasesPseudomonas aeruginosaStaphylococcus epidermidisTime FactorsAnti-Bacterial AgentsAscorbic AcidPlasma Gasesantibacterialbiofilmcold plasmaresistancevitamin C

Identifiers

PMID28275584
PMCPMC5319976
OpenAlexW2590607098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.