Evidence map›Paper›PMID 28275580›Full record

ArticleLiver cancer2017

Short-Term Results of Laparoscopic Radiofrequency Ablation Using a Multipolar System for Localized Hepatocellular Carcinoma.

Naoki Morimoto, Norio Isoda, Yoshinari Takaoka, Takuya Hirosawa, Shunji Watanabe, Toshiya Otake, Kozue Murayama, Takeshi Fujieda, Mamiko Tsukui, Natsumi Miyata and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Liver cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Naoki MorimotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Norio IsodaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Yoshinari TakaokaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Takuya HirosawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Shunji WatanabeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Toshiya OtakeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Kozue MurayamaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Takeshi FujiedaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Mamiko TsukuiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Natsumi MiyataDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Kohei OnoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Shota YamaguchiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Hironori YamamotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimMultipolar radiofrequency ablation (RFA) is feasible for the treatment of hepatocellular carcinoma (HCC) for which a large ablative area is planned, and it imposes a light physical burden on patients. Multipolar RFA via the percutaneous approach is performed in the majority of cases, but the efficacy of multipolar RFA with a laparoscopic approach has rarely been studied. This study aimed to evaluate the efficacy and safety of multipolar laparoscopic RFA (LRA) for localized HCC over the short term.

methodsFrom January 2014 to January 2016, 77 consecutive patients with 130 HCCs treated by multipolar LRA were assessed. One to three bipolar needle applicators were inserted under laparoscopic ultrasonography guidance, regardless of tumor location. We intended to achieve parallel insertions and no-touch ablation as much as possible.

resultsThe median size of the main tumor was 22 mm (range, 10-42 mm). The median follow-up time was 13.6 months (range, 3.1-24.8 months). In all cases, a sufficient ablative area was obtained as planned, without thermal injury of adjacent organs. During the follow-up period, all patients were alive with no local tumor progression, while intrahepatic recurrence distant from the primary site occurred in 7 patients. The 2-year local tumor progression-free survival rate and overall cancer-free survival rate were 100 and 81.6%, respectively. There were no procedural major complications caused prolonging the hospitalization, and all patients were discharged without subjective symptoms 4-7 days after LRA.

conclusionsMultipolar LRA was efficacious in the treatment of localized HCCs by safely achieving a good ablative area.

Indexed as

Hepatocellular carcinomaLocal ablation therapyOutcomeRadiofrequency ablationSurgery

Identifiers

PMID28275580
PMCPMC5340218
OpenAlexW2561749925

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.