Evidence map›Paper›PMID 28275459›Full record

ArticleJournal of virus eradication2017

Carbohydrate, lipid, bone and inflammatory markers in HIV-positive adolescents on antiretroviral therapy and hormonal contraception.

Nadia Kancheva Landolt, Torsak Bunupuradah, Jullapong Achalapong, Pope Kosalaraksa, Witaya Petdachai, Chaiwat Ngampiyaskul, Sasiwimol Ubolyam, Narukjaporn Thammajaruk, Stephen Kerr, Jintanat Ananworanich

Open access · goldAbstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Nadia Kancheva LandoltHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) , Bangkok , Thailand.
Torsak BunupuradahHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) , Bangkok , Thailand.
Jullapong AchalapongChiang Rai Prachanukroh Hospital , Chiang Rai , Thailand.
Pope KosalaraksaFaculty of Medicine , Khon Kaen University , Khon Kaen , Thailand.
Witaya PetdachaiPhra Chomklao Hospital Hospital , Phetchaburi , Thailand.
Chaiwat NgampiyaskulPhrapokklao Hospital , Chanthaburi , Thailand.
Sasiwimol UbolyamHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) , Bangkok , Thailand.
Narukjaporn ThammajarukHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) , Bangkok , Thailand.
Stephen KerrHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), Bangkok, Thailand; Department of Global Health, University of Amsterdam, Amsterdam Institute for Global Health and Development, the Netherlands.
Jintanat AnanworanichHIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), Bangkok, Thailand; SEARCH, Thai Red Cross AIDS Research Centre, Bangkok, Thailand; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
HIV Netherlands Australia Thailand Research Collaboration · THChiangRai Prachanukroh Hospital · THKhon Kaen University · THPrapokklao Hospital · THWalter Reed Army Institute of Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the cumulative effect of HIV antiretroviral therapy (ART) and hormonal contraception (HC) on metabolism and inflammation in HIV-positive women.

methodsWe conducted a cross-sectional assessment of markers for carbohydrate, lipid, bone metabolism, inflammation and coagulation in HIV-positive adolescents on ART and HC (

resultsThe median age was 19.5 years. Most adolescents (95%) were perinatally infected. All were on ART for a median of 9 years. HC used was progestin only (

conclusionPerinatally infected HIV-positive adolescents on ART in this pilot study had a high prevalence of metabolic abnormalities. Bone turnover markers and insulin resistance were significantly higher with HC. Research on the cumulative effect of HIV, ART and HC on metabolism and inflammation in adolescents with HIV is important in order to devise strategies for preventing and mitigating long-term comorbidities.

Identifiers

PMID28275459
PMCPMC5337422
OpenAlexW2747478000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.