Evidence map›Paper›PMID 28275303›Full record

ArticleWorld journal of gastroenterology2017

High levels of serum platelet-derived growth factor-AA and human epidermal growth factor receptor-2 are predictors of colorectal cancer liver metastasis.

Hong-Da Pan, Yi-Fan Peng, Gang Xiao, Jin Gu

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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  6. Oxidative medicine and cellular longevity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hong-Da PanHong-Da Pan, Gang Xiao, Department of Gastrointestinal Surgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
Yi-Fan PengHong-Da Pan, Gang Xiao, Department of Gastrointestinal Surgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
Gang XiaoHong-Da Pan, Gang Xiao, Department of Gastrointestinal Surgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
Jin GuHong-Da Pan, Gang Xiao, Department of Gastrointestinal Surgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
Peking University · CNBeijing Hospital · CNPeking University Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo develop predictive markers in blood for colorectal cancer liver metastasis.

methodsTwenty colorectal cancer patients were selected and divided into two groups. Group A consisted of 10 patients whose pathological TNM stage was IIIC (T3-4N2M0), while another 10 patients with synchronous liver metastasis (TNM stage IV) were recruited for group B. During the surgical procedure, a 10-mL drainage vein (DV) blood sample was obtained from the DV of the tumor-bearing segment prior to the ligation of the DV. At the same time, a 10-mL peripheral vein (PV) blood sample was collected

resultsUnivariate analysis revealed that platelet-derived growth factor AA (PDGFAA) in DV blood (dPDGFAA) (

conclusionPDGFAA in tumor drainage and HER2 in PV blood may be useful predictive factors for synchronous liver metastasis of colorectal cancer.

Indexed as

AdultAgedColorectal NeoplasmsEnzyme-Linked Immunosorbent AssayErb-b2 Receptor Tyrosine KinasesFemaleFollow-Up StudiesGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLiver NeoplasmsMaleMiddle AgedMultivariate AnalysisNeoplasm MetastasisPlatelet-Derived Growth FactorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesPlatelet-Derived Growth Factorplatelet-derived growth factor AColorectal cancerHuman epidermal growth factor receptor-2Liver metastasisPlatelet-derived growth factor AA

Identifiers

PMID28275303
PMCPMC5323448
OpenAlexW2589755280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.