ArticleHypertension research : official journal of the Japanese Society of Hypertension2017
Association between mean platelet volume and hypertension incidence.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Effects of statin therapy on mean platelet volume in patients with risk of cardiovascular diseases: a systematic review and meta-analysis.Bioscience reports · 2019Pooled it
- Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2018Pooled it
- Platelet indices and incident hypertension: effect modification by body mass index in a Chinese cohort.Journal of global health · 2026Article
- Mean platelet volume is independently associated with systolic and diastolic blood pressure: a retrospective cross-sectional study.BMC cardiovascular disorders · 2026Article
- The possible role of the vasopressin system in hematopoiesis.Scientific reports · 2024Article
- White blood cell and platelet distribution widths are associated with hypertension: data mining approaches.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- A link between white blood cell count and blood pressure levels.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Platelet Indices and Hypertension: Results from Shahedieh Cohort Study, Yazd, Iran.International journal of hypertension · 2024Article
- Cogent integration of inflammatory biomarkers and perioperative complications of thyroid surgery in thyroidology.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Mean platelet volume and the association with all-cause mortality and cardiovascular mortality among incident peritoneal dialysis patients.BMC cardiovascular disorders · 2023Article
- Platelet indices and blood pressure: a multivariable mendelian randomization study.Thrombosis journal · 2023Article
- Evaluation of Mean Platelet Volume in Children with Hypertension.International journal of hypertension · 2023Article
- Exosome Proteomics Reveals the Deregulation of Coagulation, Complement and Lipid Metabolism Proteins in Gestational Diabetes Mellitus.Molecules (Basel, Switzerland) · 2022Article
- Analysis of children with Henoch-Schonlein purpura secondary to infection.Clinical rheumatology · 2022Article
- Vitamin D Level in Patients with Consecutive Acute Coronary Syndrome Is Not Correlated with the Parameters of Platelet Activity.Journal of clinical medicine · 2022Article
- Association of Mean Platelet Volume with Risk Factors and Functional Outcome in Acute Ischemic Stroke.Journal of neurosciences in rural practice · 2021Article
- Association between central non-dipping pattern and platelet morphology in adults with type 1 diabetes without cardiovascular disease: a cross-sectional study.Scientific reports · 2021Article
- Effect of new oral anticoagulants on platelet indices in non-valvular atrial fibrillation patients.Herz · 2021Article
- Elucidation of a Causal Relationship Between Platelet Count and Hypertension: A Bi-Directional Mendelian Randomization Study.Frontiers in cardiovascular medicine · 2021Article
- Biomarkers for Antiplatelet Therapies in Acute Ischemic Stroke: A Clinical Review.Frontiers in neurology · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mean platelet volume (MPV) is increased in various cardiovascular diseases. We sought to determine the prognostic value of MPV for hypertension. We performed a retrospective cohort study. Baseline characteristics were measured in 9168 individuals without hypertension, and the follow-up period was 9 years. Hypertension was confirmed in 2881 participants during the follow-up period. When the participants were grouped according to MPV quartiles, the hazard ratio of future hypertension gradually increased across the MPV quartiles. The hazard ratios of hypertension for the II, III and IV (high) vs. I (low) quartiles of MPV were 1.13 (95% confidence interval (CI) 1.01-1.25, P=0.027), 1.25 (95% CI 1.12-1.39, P<0.001) and 1.40 (95% CI 1.26-1.55, P<0.001), respectively. In multivariate Cox regression analysis, MPV predicted hypertension independently of age, sex, platelet count, waist circumference, drinking, systolic blood pressure and creatinine levels. The present study indicated that elevated MPV is associated with increased incidence of hypertension independent of other risk factors, which suggests that platelet activity may play a role in hypertension incidence.
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