Evidence map›Paper›PMID 28275204›Full record

ArticlePediatrics2017

Impact of a National Guideline on Antibiotic Selection for Hospitalized Pneumonia.

Derek J Williams, Matthew Hall, Jeffrey S Gerber, Mark I Neuman, Adam L Hersh, Thomas V Brogan, Kavita Parikh, Sanjay Mahant, Anne J Blaschke, Samir S Shah and 2 more

Abstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Management of Pediatric Pneumonia: A Decade After the Pediatric Infectious Diseases Society and Infectious Diseases Society of America Guideline.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Derek J WilliamsDivision of Hospital Medicine, Monroe Carell Jr. Children's Hospital at Vanderbilt, derek.williams@vanderbilt.edu.
Matthew HallChildren's Hospital Association, Overland Park, Kansas.
Jeffrey S GerberDivision of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Mark I NeumanDivision of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts.
Adam L HershDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Thomas V BroganDivision of Critical Care Medicine, Seattle Children's Hospital, Seattle, Washington.
Kavita ParikhDivision of Hospital Medicine, Children's National Medical Center, Washington, DC.
Sanjay MahantDivision of Pediatric Medicine, Hospital for Sick Children, Toronto, Ontario, Canada.
Anne J BlaschkeDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Samir S ShahDivisions of Infectious Diseases, and.
Carlos G GrijalvaHealth Policy, Vanderbilt University Medical Center, Nashville, Tennessee.
Pediatric Research in Inpatient Settings Network

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Using CER to Improve Antibiotic Prescribing and Outcomes in ChildrenK08HS023320 · AHRQ · UNIVERSITY OF UTAH · PI HERSH, ADAM L. · 2014 to 2018
$801k
Development and Validation of a Clinical Prediction Rule for Pediatric PneumoniaK23AI104779 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILLIAMS, DEREK J. · 2013 to 2016
$688k
The Impact of Infant Vaccination with a 13-valent Pneumococcal Conjugate VaccineR03HS022342 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G · 2014 to 2015
$100k
AHRQ HHS K08 HS023320AHRQ HHS R03 HS022342NCATS NIH HHS UL1 TR000445NIAID NIH HHS K23 AI104779
6 · The paper itself

Abstract

backgroundWe evaluated the impact of the 2011 Pediatric Infectious Diseases Society/Infectious Diseases Society of America pneumonia guideline and hospital-level implementation efforts on antibiotic prescribing for children hospitalized with pneumonia.

methodsWe assessed inpatient antibiotic prescribing for pneumonia at 28 children's hospitals between August 2009 and March 2015. Each hospital was also surveyed regarding local implementation efforts targeting antibiotic prescribing and organizational readiness to adopt guideline recommendations. To estimate guideline impact, we used segmented linear regression to compare the proportion of children receiving penicillins in March 2015 with the expected proportion at this same time point had the guideline not been published based on a projection of a preguideline trend. A similar approach was used to estimate the short-term (6-month) impact of local implementation efforts. The correlations between organizational readiness and the impact of the guideline were estimated by using Pearson's correlation coefficient.

resultsBefore guideline publication, penicillin prescribing was rare (<10%). After publication, an absolute increase in penicillin use was observed (27.6% [95% confidence interval: 23.7%-31.5%]) by March 2015. Among hospitals with local implementation efforts (

conclusionsThe publication of the Pediatric Infectious Diseases Society/Infectious Diseases Society of America guideline was associated with sustained increases in the use of penicillins for children hospitalized with pneumonia. Local implementation efforts may have enhanced guideline adoption and appeared more relevant than hospitals' organizational readiness to change.

Indexed as

AdolescentAnti-Bacterial AgentsChildChild, PreschoolDatabases, FactualFemaleGuideline AdherenceHospitals, PediatricHumansInfantInpatientsMalePneumoniaAnti-Bacterial Agents

Identifiers

PMID28275204
PMCPMC5369677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.