Evidence map›Paper›PMID 28275191›Full record

ArticleJournal of virology2017

Quantitative Evaluation of Protein Heterogeneity within Herpes Simplex Virus 1 Particles.

Nabil El Bilali, Johanne Duron, Diane Gingras, Roger Lippé

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Modern Techniques for the Isolation of Extracellular Vesicles and Viruses.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nabil El BilaliDepartment of Pathology and Cell Biology, University of Montreal, Montreal, Quebec, Canada.
Johanne DuronDepartment of Pathology and Cell Biology, University of Montreal, Montreal, Quebec, Canada.
Diane GingrasDepartment of Pathology and Cell Biology, University of Montreal, Montreal, Quebec, Canada.
Roger LippéDepartment of Pathology and Cell Biology, University of Montreal, Montreal, Quebec, Canada roger.lippe@umontreal.ca.ORCID http://orcid.org/0000-0001-5066-3070
Université de Montréal · CA

Funding

CIHR MOP258030
6 · The paper itself

Abstract

Several virulence genes have been identified thus far in the herpes simplex virus 1 genome. It is also generally accepted that protein heterogeneity among virions further impacts viral fitness. However, linking this variability directly with infectivity has been challenging at the individual viral particle level. To address this issue, we resorted to flow cytometry (flow virometry), a powerful approach we recently employed to analyze individual viral particles, to identify which tegument proteins vary and directly address if such variability is biologically relevant. We found that the stoichiometry of the U

Indexed as

AnimalsBlotting, WesternChlorocebus aethiopsFlow CytometryGenes, ViralHerpes Simplex Virus Protein Vmw65Herpesvirus 1, HumanRNA, Small InterferingVero CellsViral Structural ProteinsVirionVirus AssemblyHerpes Simplex Virus Protein Vmw65herpes simplex virus type 1 protein VP22RNA, Small InterferingViral Structural ProteinsFACSflow cytometryflow virometryherpes simplex virusheterogeneityHSV-1tegumentviral particleVP16VP22

Identifiers

PMID28275191
PMCPMC5411592
OpenAlexW2594314141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.