Evidence map›Paper›PMID 28275185›Full record

ArticleJournal of virology2017

Broadly Reactive Anti-Respiratory Syncytial Virus G Antibodies from Exposed Individuals Effectively Inhibit Infection of Primary Airway Epithelial Cells.

B Cortjens, E Yasuda, X Yu, K Wagner, Y B Claassen, A Q Bakker, J B M van Woensel, T Beaumont

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 73 citations in OpenAlex.

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  10. Polarization of the memory B-cell response.Journal of leukocyte biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

B CortjensPaediatric Intensive Care, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-0289-4250
E YasudaAIMM Therapeutics, Academic Medical Center, Amsterdam, The Netherlands.
X YuDepartment of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands.
K WagnerAIMM Therapeutics, Academic Medical Center, Amsterdam, The Netherlands.
Y B ClaassenAIMM Therapeutics, Academic Medical Center, Amsterdam, The Netherlands.
A Q BakkerAIMM Therapeutics, Academic Medical Center, Amsterdam, The Netherlands.
J B M van WoenselPaediatric Intensive Care, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
T BeaumontAIMM Therapeutics, Academic Medical Center, Amsterdam, The Netherlands tbeaumont@aimmtherapeutics.com.
Amsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) causes severe respiratory disease in young children. Antibodies specific for the RSV prefusion F protein have guided RSV vaccine research, and in human serum, these antibodies contribute to >90% of the neutralization response; however, detailed insight into the composition of the human B cell repertoire against RSV is still largely unknown. In order to study the B cell repertoire of three healthy donors for specificity against RSV, CD27

Indexed as

AdultAntibodies, ViralAntibody-Dependent Cell CytotoxicityB-LymphocytesBronchiCells, CulturedEpithelial CellsEpitopesGlycoproteinsHealthy VolunteersHumansImmunoglobulin GImmunologic MemoryPhagocytosisRespiratory MucosaRespiratory Syncytial VirusesAntibodies, ViralEpitopesGlycoproteinsImmunoglobulin GTumor Necrosis Factor Receptor Superfamily, Member 7antibody functionantibody repertoireneutralizationrespiratory syncytial virusRSV G protein

Identifiers

PMID28275185
PMCPMC5411575
OpenAlexW2593076788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.