Evidence map›Paper›PMID 28275163›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Axonal Degeneration in Retinal Ganglion Cells Is Associated with a Membrane Polarity-Sensitive Redox Process.

Mohammadali Almasieh, Maria-Magdalena Catrinescu, Loïc Binan, Santiago Costantino, Leonard A Levin

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  5. Review
  6. Article
  7. A time window for rescuing dying retinal ganglion cells.Cell communication and signaling : CCS · 2024
    Article
  8. Review
  9. Cognitive Impairment in Multiple Sclerosis.Bioengineering (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Axonal spheroids in neurodegeneration.Molecular and cellular neurosciences · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohammadali AlmasiehMaisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec H1T 2M4, Canada.ORCID 0000-0003-1533-6642
Maria-Magdalena CatrinescuMaisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Loïc BinanMaisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Santiago CostantinoMaisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Leonard A LevinMaisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec H1T 2M4, Canada, leonard.levin@mcgill.ca.ORCID 0000-0002-1399-250X
Hôpital Maisonneuve-Rosemont · CAUniversity of Wisconsin–Madison · US

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6M
Development of redox-active therapies for ischemic optic neuropathyR21EY025074 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI LEVIN, LEONARD A · 2015 to 2016
$421k
NEI NIH HHS P30 EY016665NEI NIH HHS R21 EY025074
6 · The paper itself

Abstract

Axonal degeneration is a pathophysiological mechanism common to several neurodegenerative diseases. The slow Wallerian degeneration (Wld

Indexed as

AnimalsAnimals, NewbornAxotomyCell MembraneCell PolarityCells, CulturedFemaleMaleOxidation-ReductionPregnancyRatsRats, Sprague-DawleyRats, TransgenicRetinal Ganglion CellsWallerian Degenerationaxonal degenerationaxon membranephosphatidylserineredoxWallerian degeneration slow

Identifiers

PMID28275163
PMCPMC5394899
OpenAlexW2593620534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.