ArticleScience translational medicine2017
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Science translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 137 papers.
0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed, 219 citations in OpenAlex.
- Remission in Crohn's disease is accompanied by alterations in the gut microbiota and mucins production.Scientific reports · 2019Trial
- Trial
- The role ofmBio · 2026Article
- Innate immune recognition ofInfection and immunity · 2026Article
- Intestinal epithelial SETD2 maintains gut microbial homeostasis to attenuate colitis.Clinical and translational medicine · 2026Article
- Saccharomycetes and Malassezia fungi associate with early-life gut maturation and allergic disease risk in childhood.Nature communications · 2026Article
- A Randomized Controlled Trial Comparing Soy-Pea Protein to Animal Protein in Adults with Crohn's Disease.medRxiv : the preprint server for health sciences · 2026Article
- Gut mycobiota alteration contributes to the pathogenesis of Pneumocystis pneumonia.Journal of translational medicine · 2026Article
- Biological Deacidification and High-Value Transformation of Acidic Citrus Pulp by Multi-Microbial Fermentation.Foods (Basel, Switzerland) · 2026Article
- Article
- Characteristics of the gut mycobiome in patients with membranous nephropathy.Scientific reports · 2026Article
- Untargeted Metabolomic Analysis of Cell-Free Supernatants (CFSs) from Different Clinical Isolates ofJournal of fungi (Basel, Switzerland) · 2026Article
- Phthalates exposure and serum uric acid level in patients with Crohn's disease: A cross-sectional study.PloS one · 2026Article
- Age-specific alterations of the gut mycobiome in patients with myalgic encephalomyelitis/chronic fatigue syndrome and identification of potential diagnostic biomarkers.BMC microbiology · 2025Article
- Review
- Xanthine Oxidase-Dependent Activation of NLPR3 Inflammasome in Epithelial Cells Sustains Inflammation in Inflammatory Bowel Disease.Inflammatory bowel diseases · 2025Article
- Neuroimmune Crossroads: Pathophysiological Links Between Bipolar Disorder and Inflammatory Bowel Disease.Actas espanolas de psiquiatria · 2025Review
- A role for gut mycobiome and altered fungal-bacterial interactions in women with endometriosis†.Biology of reproduction · 2025Article
- The role of the mycobiome in host physiology and disease: insights from rodent models.Lab animal · 2025Review
- Cystic fibrosis and inflammatory bowel disease: parallels in gut physiology and microbiota.Journal of bacteriology · 2025Review
77 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 1 institution in 1 country.
Tyson R ChiaroDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-8132-5186
Ray SotoDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
W Zac StephensDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-8072-9023
Jason L KubinakDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Charisse PetersenDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Lasha GogokhiaDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0003-3652-0377
Rickesha BellDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-0554-0730
Julio C DelgadoDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-3455-1711
James CoxMetabolomics Core, University of Utah Health Sciences Center, Salt Lake City, UT 84112, USA.ORCID 0000-0002-5977-2350
Warren VothDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0003-0632-6979
Jessica BrownDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-3255-1486
David J StillmanDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0002-5268-2416
Ryan M O'ConnellDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Anne E TeboDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.ORCID 0000-0001-9553-298X
June L RoundDivision of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. june.round@path.utah.edu.ORCID 0000-0002-7158-9874
University of Utah · US
Funding
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Temitope O. Keku · 1985 to 2026
$30.5MNational Gnotobiotic Rodent Resource CenterP40OD010995 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ryan B Sartor · 2012 to 2026
$9.7MBiochemical, Genetic, and Genomic Analysis of Nucleosome Reorganization by FACTR01GM064649 · NIGMS · UNIVERSITY OF UTAH · PI FORMOSA, TIMOTHY G · 2002 to 2022
$6.4MTRAINING PROGRAM IN GENETICST32GM007464 · NIGMS · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J., STANFIELD, GILLIAN · 1985 to 2020
$6.1MTraining Program in Microbial PathogenesisT32AI055434 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A, PLANELLES, VICENTE · 2004 to 2025
$6.0MDeveloping therapies to target the microbiotaDP2AT008746 · NCCIH · UNIVERSITY OF UTAH · PI ROUND, JUNE LOUISE · 2014 to 2014
$2.2MUtilizing TALEN technology to regulate human microRNA'sDP2GM111099 · NIGMS · UNIVERSITY OF UTAH · PI O'CONNELL, RYAN M · 2013 to 2013
$2.2MInvestigate the Role of Micro-RNA 155 in Myeloid Development during InflammationR00HL102228 · NHLBI · UNIVERSITY OF UTAH · PI O'CONNELL, RYAN M · 2011 to 2013
$654kExploring the function of a novel, microbiota-regulated gene in T cellsR21AI109122 · NIAID · UNIVERSITY OF UTAH · PI ROUND, JUNE LOUISE · 2014 to 2015
$410kHIV VACCINE PRODUCTIONN01AI095375 · NIAID · SRI INTERNATIONAL · PI KUNG, ADA P · 1999 to 2000
$61kNCCIH NIH HHS DP2 AT008746NHLBI NIH HHS R00 HL102228NIAID NIH HHS N01 AI095375NIAID NIH HHS R21 AI109122NIAID NIH HHS T32 AI055434NIDDK NIH HHS P30 DK034987NIGMS NIH HHS DP2 GM111099NIGMS NIH HHS R01 GM064649NIGMS NIH HHS T32 GM007464NIH HHS P40 OD010995
Abstract
The commensal microbiota has an important impact on host health, which is only beginning to be elucidated. Despite the presence of fungal, archaeal, and viral members, most studies have focused solely on the bacterial microbiota. Antibodies against the yeast
Indexed as
Disease ProgressionGastrointestinal MicrobiomeHost-Pathogen InteractionsAnimalsAntibodies, FungalColitisColony Count, MicrobialDisease Models, AnimalFemaleHumansIntestinal MucosaMaleMice, Inbred C57BLPurinesRhodotorulaSaccharomyces cerevisiaeAntibodies, FungalPurinesUric Acid
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.