Evidence map›Paper›PMID 28275064›Full record

ArticleJournal of the American Heart Association2017

Obesity Increases Risk-Adjusted Morbidity, Mortality, and Cost Following Cardiac Surgery.

Ravi K Ghanta, Damien J LaPar, Qianzi Zhang, Vishal Devarkonda, James M Isbell, Leora T Yarboro, John A Kern, Irving L Kron, Alan M Speir, Clifford E Fonner and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 137 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ravi K GhantaBaylor College of Medicine, Houston, TX ghanta@bcm.edu.
Damien J LaParUniversity of Virginia, Charlottesville, VA.
Qianzi ZhangBaylor College of Medicine, Houston, TX.
Vishal DevarkondaUniversity of Virginia, Charlottesville, VA.
James M IsbellUniversity of Virginia, Charlottesville, VA.
Leora T YarboroUniversity of Virginia, Charlottesville, VA.
John A KernUniversity of Virginia, Charlottesville, VA.
Irving L KronUniversity of Virginia, Charlottesville, VA.
Alan M SpeirInova Heart and Vascular Institute, Falls Church, VA.
Clifford E FonnerVirginia Cardiac Surgery Quality Initiative, Charlottesville, VA.
Gorav AilawadiUniversity of Virginia, Charlottesville, VA.
University of Virginia · USBaylor College of Medicine · USAlaska Heart and Vascular Institute · USBon Secours Heart & Vascular Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the epidemic rise in obesity, few studies have evaluated the effect of obesity on cost following cardiac surgery. We hypothesized that increasing body mass index (BMI) is associated with worse risk-adjusted outcomes and higher cost. METHODS AND

resultsMedical records for 13 637 consecutive patients who underwent coronary artery bypass grafting (9702), aortic (1535) or mitral (837) valve surgery, and combined valve-coronary artery bypass grafting (1663) procedures were extracted from a regional Society of Thoracic Surgeons certified database. Patients were stratified by BMI: normal to overweight (BMI 18.5-30), obese (BMI 30-40), and morbidly obese (BMI >40). Differences in outcomes and cost were compared between BMI strata and also modeled as a continuous function of BMI with adjustment for preoperative risk using Society of Thoracic Surgeons predictive risk indices. Morbidly obese patients incurred nearly 60% greater observed mortality than normal weight patients. Moreover, morbidly obese patients had greater than 2-fold increase in renal failure and 6.5-fold increase in deep sternal wound infection. After risk adjustment, a significant association was found between BMI and mortality (

conclusionsHigher BMI is associated with increased mortality, major morbidity, and cost for hospital care. As such, BMI should be more strongly considered in risk assessment and resource allocation.

Indexed as

Cardiac Surgical ProceduresHealth Care CostsMortalityAgedAortic ValveCoronary Artery BypassFemaleHeart Valve Prosthesis ImplantationHospitalizationHumansLinear ModelsMaleMiddle AgedMitral ValveMultilevel AnalysisObesitycomplicationcostobesitysurgery

Identifiers

PMID28275064
PMCPMC5523989
OpenAlexW2594741583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.