Evidence map›Paper›PMID 28275057›Full record

ArticleJournal of neurophysiology2017

Activity-dependent increases in [Ca

Bjoern Ch Ludwar, Colin G Evans, Monica Cambi, Elizabeth C Cropper

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bjoern Ch LudwarDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; and.
Colin G EvansDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; and.
Monica CambiDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; and.
Elizabeth C CropperDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; and elizabeth.cropper@gmail.com.
Allen Institute for Brain Science · USIcahn School of Medicine at Mount Sinai · US

Funding

NEURAL BASIS OF BEHAVIORAL PLASTICITY IN A SIMPLE SYSTEMR01MH051393 · NIMH · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI CROPPER, ELIZABETH C · 1993 to 2016
$6.1M
Neural Basis of Behavioral ArousalR01NS066587 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CROPPER, ELIZABETH C · 2009 to 2023
$5.2M
NIMH NIH HHS R01 MH051393NINDS NIH HHS R01 NS066587
6 · The paper itself

Abstract

In a type of short-term plasticity that is observed in a number of systems, synaptic transmission is potentiated by depolarizing changes in the membrane potential of the presynaptic neuron before spike initiation. This digital-analog form of plasticity is graded. The more depolarized the neuron, the greater the increase in the efficacy of synaptic transmission. In a number of systems, including the system presently under investigation, this type of modulation is calcium dependent, and its graded nature is presumably a consequence of a direct relationship between the intracellular calcium concentration ([Ca

Indexed as

Analysis of VarianceAnimalsAplysiaCalciumCations, DivalentFemaleGanglia, InvertebrateIntracellular SpaceMaleMechanoreceptorsMicroelectrodesNeuronal PlasticitySynapsesSynaptic TransmissionTissue Culture TechniquesVoltage-Sensitive Dye ImagingCalciumCations, DivalentAplysiacalciuminvertebratesynaptic plasticitytransmitter release

Identifiers

PMID28275057
PMCPMC5454465
OpenAlexW2594432389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.