Evidence map›Paper›PMID 28274930›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Nitric oxide reduces paracellular resistance in rat thick ascending limbs by increasing Na

Casandra M Monzon, Rossana Occhipinti, Omar P Pignataro, Jeffrey L Garvin

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Recent advances in renal epithelial transport.American journal of physiology. Renal physiology · 2019
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Casandra M MonzonDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio; casandra.monzon@case.edu.
Rossana OcchipintiDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio.
Omar P PignataroDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales-Universidad de Buenos Aires, Buenos Aires, Argentina; and.
Jeffrey L GarvinDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio.
Case Western Reserve University · USConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

Salt-Sensitive Hypertension: Role of Renal SuperoxideR01HL070985 · NHLBI · HENRY FORD HEALTH SYSTEM · PI Jeffrey L. Garvin · 2002 to 2026
$6.3M
Acid secretion and intracellular pH regulation in proximal-tubule cellsK01DK107787 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI OCCHIPINTI, ROSSANA · 2015 to 2019
$541k
NHLBI NIH HHS R01 HL070985NIDDK NIH HHS K01 DK107787
6 · The paper itself

Abstract

About 50% of the Na

Indexed as

Renal ReabsorptionAnimalsArginineBiological TransportChloridesCyclic GMPElectric ImpedanceEnzyme InhibitorsIn Vitro TechniquesLoop of HenleMaleModels, BiologicalNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthasePerfusionArginineChloridesCyclic GMPEnzyme InhibitorsNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseSodiumkidneynitric oxideparacellular permeabilitysodium transport

Identifiers

PMID28274930
PMCPMC5495890
OpenAlexW2594072470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.