Evidence map›Paper›PMID 28274922›Full record

ArticleAmerican journal of physiology. Cell physiology2017

Membrane lipid rafts are disturbed in the response of rat skeletal muscle to short-term disuse.

Alexey M Petrov, Violetta V Kravtsova, Vladimir V Matchkov, Alexander N Vasiliev, Andrey L Zefirov, Alexander V Chibalin, Judith A Heiny, Igor I Krivoi

Open access · goldAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Alexey M PetrovDepartment of Normal Physiology, Kazan State Medical University, Kazan, Russia.
Violetta V KravtsovaDepartment of General Physiology, St. Petersburg State University, St. Petersburg, Russia.
Vladimir V MatchkovDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Alexander N VasilievDepartment of General Physiology, St. Petersburg State University, St. Petersburg, Russia.
Andrey L ZefirovDepartment of Normal Physiology, Kazan State Medical University, Kazan, Russia.
Alexander V ChibalinDepartment of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden; and.
Judith A HeinyDepartment of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Igor I KrivoiDepartment of General Physiology, St. Petersburg State University, St. Petersburg, Russia; iikrivoi@gmail.com.
St Petersburg University · RUKazan State Medical University · RUAarhus University · DKKarolinska Institutet · SEUniversity of Cincinnati Medical Center · US

Funding

Isoform-specific roles of the Na,K-ATPase in skeletal muscleR01AR063710 · NIAMS · UNIVERSITY OF CINCINNATI · PI HEINY, JUDITH A, LINGREL, JERRY B · 2013 to 2017
$2.2M
NIAMS NIH HHS R01 AR063710
6 · The paper itself

Abstract

Marked loss of skeletal muscle mass occurs under various conditions of disuse, but the molecular and cellular mechanisms leading to atrophy are not completely understood. We investigate early molecular events that might play a role in skeletal muscle remodeling during mechanical unloading (disuse). The effects of acute (6-12 h) hindlimb suspension on the soleus muscles from adult rats were examined. The integrity of plasma membrane lipid rafts was tested utilizing cholera toxin B subunit or fluorescent sterols. In addition, resting intracellular Ca

Indexed as

AnimalsCalciumCalcium SignalingCholesterolHindlimb SuspensionMaleMembrane MicrodomainsMuscle, SkeletalMuscular Disorders, AtrophicRatsRats, WistarCalciumCholesterolcholesterolhindlimb suspensionintracellular calciumlipid raftsskeletal muscle disuse

Identifiers

PMID28274922
PMCPMC5451522
OpenAlexW2592720139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.