ArticlePharmaceutical biology2017
Effect of Spirulina platensis ingestion on the abnormal biochemical and oxidative stress parameters in the pancreas and liver of alloxan-induced diabetic rats.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 45 citations in OpenAlex.
- Bioactivity of Marine-Derived Peptides and Proteins: A Review.Marine drugs · 2025Review
- Modulatory role ofFrontiers in pharmacology · 2025Article
- Spirulina (Nutrients · 2024Article
- Antioxidant and Antidiabetic Activity of Algae.Life (Basel, Switzerland) · 2023Review
- The effect ofFood science & nutrition · 2022Article
- Antidiabetic Potential and Antioxidant Activity ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Article
- Isolation, Purification, Characterization, and Immunomodulatory Activity Analysis of α-Glucans fromACS omega · 2021Article
- Effect of spirulina and chlorella alone and combined on the healing process of diabetic wounds: an experimental model of diabetic rats.Journal of diabetes and metabolic disorders · 2021Article
- Edible Microalgae and Their Bioactive Compounds in the Prevention and Treatment of Metabolic Alterations.Nutrients · 2021Review
- Evaluation of the anti-inflammatory and antioxidant effects of the microalgaeJournal of diabetes and metabolic disorders · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPrevious studies have shown that Spirulina platensis Gomont (Phormidiaceae) (SP) extract has beneficial effects on many disease conditions. The putative protective effects of SP were investigated in diabetic rats.
objectiveThe current study investigates the antioxidant effects of SP in diabetic Wistar rats. MATERIALS AND
methodsAlloxan monohydrate (150 mg/kg body weight) was intraperitoneally administrated to induce diabetes. An aqueous suspension of SP powder in distillate water (10% w/v) was administrated orally by gavage (1 mL/day) for 50 days. Histopathological, biochemical and antioxidant analyses were performed. Glycemia, liver function and HOMA-IR were assessed using Spinreact and ELISA kits.
resultsSP exhibited high-antioxidant activity. The IC DISCUSSION AND
conclusionThese results showed that SP has high antioxidant activity, free radical scavenging, antihyperglycemic and hepatoprotective effects in diabetes.
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Registered trials
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