ArticleJournal of clinical and diagnostic research : JCDR2017
Comparison of Cord Blood Lipid Profile in Preterm Small for Gestational Age and Appropriate for Gestational Age Newborns.
Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- An encyclopedia of the cord blood metabolome reveals maternal-fetal interactions and disease risk.Cell reports. Medicine · 2026Article
- Significance of lipids, lipoproteins, and apolipoproteins during the first 14-16 months of life.European heart journal · 2023Article
- Characterization of lipoproteins and associated lipidome in very preterm infants: a pilot study.Pediatric research · 2023Article
- Hyperemesis gravidarum severity, enteral tube feeding and cardiometabolic markers in offspring cord blood.The British journal of nutrition · 2022Article
- Associations of Cord Blood Lipids with Childhood Adiposity at the Age of Three Years: A Prospective Birth Cohort Study.Metabolites · 2022Article
- Metabolic flexibility during late pregnancy is associated with neonatal adiposity.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021Observational
- Associations of Longitudinal Fetal Growth Patterns With Cardiometabolic Factors at Birth.Frontiers in endocrinology · 2021Article
- Increased risk for early hypertriglyceridemia in small for gestational age preterm infants.European journal of pediatrics · 2020Article
- A multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism.Metabolism: clinical and experimental · 2020Article
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Authors and funding
4 authors.
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Abstract
introductionCoronary heart disease is one of the major causes of morbidity and mortality in current era. The roots of this epidemic have been traced to as early as foetal life by foetal origin hypothesis. There are a few studies which have compared the cord blood lipid profile of preterm and term babies and thereby leading a path to primordial prevention of chronic diseases.
aimTo study cord blood lipid profile of preterm appropriate for gestational age and preterm small for gestational age neonates and compare atherogenic index of both groups. MATERIALS AND
methodsThis cross-sectional study was conducted in 109 preterm infants. Cord blood samples were collected from placental side of umbilical cord at birth and analyzed for lipid profile which includes serum cholesterol, triglycerides, Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL) and apolipoproteins which include ApoA1, Apo B.
resultsPreterm Small for Gestational Age (SGA) neonates had statistically significant higher values of triglycerides, Apo B and atherogenic index compared to preterm Appropriate for Gestational Age (AGA) neonates. Other measured lipid levels were not statistically significant, though the values were higher than reference ranges for term babies.
conclusionPrematurity as a factor associated with a more atherogenic lipid profile is re-affirmed and SGA as an additional risk factor has been proven giving scope for future research and primordial prevention.
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