ArticleJournal of clinical and diagnostic research : JCDR2017
Neurological Manifestations in Systemic Lupus Erythematosus: A Single Centre Study from North East India.
Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Psychosis in patients with systematic lupus erythematosus: A systematic literature review and meta-analysis.Lupus · 2026Pooled it
- Pooled it
- From Nerve to Autoimmunity: Acute Guillain-Barré Syndrome in a 4-Year-Old with Early-Onset Pediatric Systemic Lupus Erythematosus.Open access rheumatology : research and reviews · 2026Article
- Examining the Effectiveness of Acceptance and Commitment Therapy on the Cognitive Functions of Patients with Systemic Lupus Erythematosus.Iranian journal of psychiatry · 2026Article
- Review
- Acute Motor Axonal Neuropathy in Lupus Nephritis.Cureus · 2024Article
- Article
- Genome-Wide Scanning of Potential Hotspots for Adenosine Methylation: A Potential Path to Neuronal Development.Life (Basel, Switzerland) · 2021Article
- A Rare Case with Systemic Lupus Erythematosus Manifested by two Different Neurologic Entities; Guillain Barre Syndrome and Posterior Reversible Encephalopathy Syndrome.Mediterranean journal of rheumatology · 2020Article
- A De Novo Frameshift Mutation in TNFAIP3 Impairs A20 Deubiquitination Function to Cause Neuropsychiatric Systemic Lupus Erythematosus.Journal of clinical immunology · 2019Article
- Neuropsychiatric lupus: new mechanistic insights and future treatment directions.Nature reviews. Rheumatology · 2019Review
- Guillain-Barre syndrome as the first manifestation of juvenile systemic lupus erythematosus: a case report.Open access rheumatology : research and reviews · 2019Article
- Aneurysmal subarachnoid hemorrhage in a patient with dual autoimmune disorders. Perioperative challenges and management.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNeurological manifestations although common in Systemic Lupus Erythematosus (SLE), are often not recognized due to their diversed and varied presentation. Therefore, the study was planned to highlight the pattern of neurological involvement in SLE to help in early recognition.
aimTo study the pattern of neurological involvement in SLE and its correlation with disease activity and different investigation. MATERIALS AND
methodsThis hospital based prospective observational study was carried out from August 2009 to July 2010. Diagnosed cases of SLE [based upon American Rheumatism Association (ARA) criteria] who presented with neurological manifestations at the time of diagnosis or develop during the course of the disease were included in the study. They were assessed clinically and investigated with neuroimaging and neurophysiological tests as applicable.
resultsIn total, 52 consecutive patients with SLE were evaluated, 92% were female. The most common age group was 21 to 25 years. Nervous system involvement was found in 19 (36.54%) patients. Cognitive impairment was the most frequent manifestation, present in 11 (57.89%) patients followed by seizure disorder in eight patients (42.1%). Peripheral neuropathy was diagnosed in eight (42.1%), acute confusional state in six (31.57%) and headache and depression was diagnosed in five (26.31%) patients each. Less common manifestations were psychosis, movement disorder and aseptic meningitis. Percentage of neurological manifestations directly correlated with disease activity. A significant difference was found in Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score between the patients with Neuro Psychiatric Systemic Lupus Erythematosus (NPSLE) and those without NPSLE (32.42±16.34 Vs 17.3±10.6).
conclusionNeurological involvement in SLE is seen relatively early in the course of the disease with cognitive impairment being the most common manifestation and correlate with disease activity.
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