Evidence map›Paper›PMID 28273964›Full record

ArticleJournal of clinical and diagnostic research : JCDR2017

Biofilm Formation by Drug Resistant Enterococci Isolates Obtained from Chronic Periodontitis Patients.

Sonia Bhonchal Bhardwaj, Manjula Mehta, Shaveta Sood, Jyoti Sharma

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Development of a Magnetic Bead-Based Method for Specific Detection ofJournal of microbiology and biotechnology · 2023
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  5. Role of Biofilm in Bacterial Infection and Antimicrobial Resistance.JNMA; journal of the Nepal Medical Association · 2022
    Article
  6. Prevalence and Antibiotic Susceptibility Trends of SelectedAntibiotics (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Encapsulation of a NovelJournal of global infectious diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sonia Bhonchal BhardwajAssistant Professor, Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital , Chandigarh, India .
Manjula MehtaAssociate Professor, Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital , Chandigarh, India .
Shaveta SoodAssistant Professor, Department of Periodontics, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital , Chandigarh, India .
Jyoti SharmaAssistant Professor, Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital , Chandigarh, India .
Veer Bahadur Singh Purvanchal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEnterococci are an important cause of opportunistic nosocomial infections and several multidrug resistant strains have emerged. The severity of periodontal diseases is managed by reduction in the pathogenic bacteria. There is a need to assess the prevalence and antibiotic susceptibility of enterococci colonizing the periodontal pocket and correlate its biofilm formation ability because oral biofilms provide a protective environment and are a reservoir of bacterial colonization of the gingival crevice.

aimTo investigate possible association between antibiotic susceptibility and biofilm formation in enterococci isolates from chronic periodontitis patients. MATERIALS AND

methodsThis retrospective study was conducted at Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Punjab University, Chandigarh from January 2015 to October 2015. Sterile paper points were inserted in the periodontal pocket of 100 subjects and put in a transport media. Forty -six isolates were identified as enterococci. The isolates were further examined for their ability to form biofilm by microtitre plate assay and antimicrobial susceptibility testing was done by disc diffusion method for clinically relevant antibiotics.

resultsSignificant relationship (p<0.001) was found between biofilm production with antibiotic resistance to Vancomycin, Erythromycin, Ciprofloxacin, Tiecoplanin, Amoxycillin and Gentamycin.

conclusionThe study demonstrates a high propensity among the isolates of Enterococci to form biofilm and a significant association of biofilm with multiple drug resistance.

Indexed as

Antibiotic resistanceBiofilm matrixEnterococcusPeriodontal disease

Identifiers

PMID28273964
PMCPMC5324409
OpenAlexW2587462805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.