Evidence map›Paper›PMID 28273905›Full record

ArticleScientific reports2017

NKG2D modulates aggravation of liver inflammation by activating NK cells in HBV infection.

Yadong Wang, Wei Wang, Chuan Shen, Yong Wang, Mingjing Jiao, Weiyan Yu, Hongzhu Yin, Xiaobo Shang, Qianfei Liang, Caiyan Zhao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Potential therapies for acute-on-chronic liver failure.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  7. Review
  8. Article
  9. Macrophage pathology in hepatotoxicity.Journal of toxicologic pathology · 2023
    Review
  10. Innate immunity and early liver inflammation.Frontiers in immunology · 2023
    Review
  11. Review
  12. The antifibrotic role of natural killer cells in liver fibrosis.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  13. Review
  14. Article
  15. Review
  16. Liver-Resident Bystander CD8Gastroenterology · 2021
    Article
  17. Innate immunity and HBV persistence.Current opinion in virology · 2021
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yadong WangDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Wei WangDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Chuan ShenDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Yong WangDepartment of Scientific Research, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Mingjing JiaoDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Weiyan YuDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Hongzhu YinDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Xiaobo ShangDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Qianfei LiangDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Caiyan ZhaoDepartment of Infectious Diseases, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, China. zhaocy2005@163.com.
Hebei Medical University · CNThird Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is thought to be an immune-mediated liver disease. The mechanisms underlying natural killer (NK) cell group 2D receptor (NKG2D) that activates NK cells and participates in anti-HBV immunity and immunopathology has not been thoroughly elucidated. Peripheral NKG2D

Indexed as

AdultCoculture TechniquesDisease ProgressionFemaleGranzymesHepatitis B, ChronicHepatitis B virusHep G2 CellsHumansInterferon-gammaKiller Cells, NaturalLiverMaleMiddle AgedNK Cell Lectin-Like Receptor Subfamily KPerforinGranzymesIFNG protein, humanInterferon-gammaKLRK1 protein, humanNK Cell Lectin-Like Receptor Subfamily KPerforinTNF protein, humanTumor Necrosis Factor-alpha

Identifiers

PMID28273905
PMCPMC5427972
OpenAlexW2592489202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.