Evidence map›Paper›PMID 28273855›Full record

Trial reportNutrients2017

Integration of Traditional and Metabolomics Biomarkers Identifies Prognostic Metabolites for Predicting Responsiveness to Nutritional Intervention against Oxidative Stress and Inflammation.

You Jin Kim, Iksoo Huh, Ji Yeon Kim, Saejong Park, Sung Ha Ryu, Kyu-Bong Kim, Suhkmann Kim, Taesung Park, Oran Kwon

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Biomarkers of Berry Intake: Systematic Review Update.Journal of agricultural and food chemistry · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

You Jin KimDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea. eugene841226@gmail.com.
Iksoo HuhDepartment of Statistics, Seoul National University, Seoul 08826, Korea. huhixoo@gmail.com.
Ji Yeon KimDepartment of Food Science and Technology, Seoul National University of Science and Technology, Seoul 01811, Korea. jiyeonk@seoultech.ac.kr.
Saejong ParkDepartment of Sport Science, Korea Institute of Sport Science, Seoul 01794, Korea. saejpark@sports.re.kr.
Sung Ha RyuCollege of Pharmacy, Dankook University, Chungnam 31116, Korea. shryu@glpt.co.kr.
Kyu-Bong KimCollege of Pharmacy, Dankook University, Chungnam 31116, Korea. kyubong@dankook.ac.kr.
Suhkmann KimDepartment of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan 46241, Korea. suhkmann@pusan.ac.kr.
Taesung ParkDepartment of Statistics, Seoul National University, Seoul 08826, Korea. tspark@stats.snu.ac.kr.
Oran KwonDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea. orank@ewha.ac.kr.
Dankook University · KREwha Womans University · KRSeoul National University · KRKorea Institute of Sport Science · KRPusan National University · KRSeoul National University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various statistical approaches can be applied to integrate traditional and omics biomarkers, allowing the discovery of prognostic markers to classify subjects into poor and good prognosis groups in terms of responses to nutritional interventions. Here, we performed a prototype study to identify metabolites that predict responses to an intervention against oxidative stress and inflammation, using a data set from a randomized controlled trial evaluating Korean black raspberry (KBR) in sedentary overweight/obese subjects. First, a linear mixed-effects model analysis with multiple testing correction showed that four-week consumption of KBR significantly changed oxidized glutathione (GSSG,

Indexed as

MetabolomicsOxidative StressAdultBiomarkersBody Mass IndexDietErythrocytesFemaleGlutathioneGlycineHumansInflammationInterleukin-6Linear ModelsMagnetic Resonance SpectroscopyMalondialdehydeBiomarkersGlutathioneGlycineIL6 protein, humanInterleukin-6Malondialdehydephenylacetylglycineinflammationmetabolomicsoxidative stressprognostic markersedentary overweight/obese adults

Identifiers

PMID28273855
PMCPMC5372896
OpenAlexW2594576998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.