ArticleMarine drugs2017
Chitosan-Based Nanomedicine to Fight Genital Candida Infections: Chitosomes.
Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 57 citations in OpenAlex.
- Advances in Nanostructured Lipid Carriers for Colorectal Cancer Treatment: A Comprehensive Review.Current drug delivery · 2026Review
- Novel Targets and Nanotechnology Approaches in Treating Vulvovaginal Candidiasis: Insights into Host-Microbe Interactions and Immunotherapy.Current pharmaceutical design · 2026Review
- Fungal-Derived Chitosan fromMaterials (Basel, Switzerland) · 2025Article
- A landscape of recent advances in lipid nanoparticles and their translational potential for the treatment of solid tumors.Bioengineering & translational medicine · 2024Review
- Emerging Polymer-Based Nanosystem Strategies in the Delivery of Antifungal Drugs.Pharmaceutics · 2023Review
- Lecithin and Chitosan as Building Blocks in Anti-Pharmaceuticals (Basel, Switzerland) · 2023Article
- Vaginal Sheets withGels (Basel, Switzerland) · 2023Article
- Development of Ulvan-Containing Liposomes as Antibacterial Drug Delivery Platforms.Journal of functional biomaterials · 2022Article
- Novel Metoprolol-Loaded Chitosan-Coated Deformable Liposomes in Thermosensitive In Situ Gels for the Management of Glaucoma: A Repurposing Approach.Gels (Basel, Switzerland) · 2022Article
- Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review.Marine drugs · 2022Review
- The Expanded Role of Chitosan in Localized Antimicrobial Therapy.Marine drugs · 2021Review
- Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability.Molecules (Basel, Switzerland) · 2021Review
- Manufacturing and Examination of Vaginal Drug Delivery System by FDM 3D Printing.Pharmaceutics · 2021Article
- New perspectives on the topical management of recurrent candidiasis.Drug delivery and translational research · 2021Review
- Chitosomes-In-Chitosan Hydrogel for Acute Skin Injuries: Prevention and Infection Control.Marine drugs · 2021Article
- Recent Biomedical Approaches for Chitosan Based Materials as Drug Delivery Nanocarriers.Pharmaceutics · 2021Review
- Nanomaterials for the Diagnosis and Treatment of Urinary Tract Infections.Nanomaterials (Basel, Switzerland) · 2021Review
- The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations.Pharmaceutics · 2020Article
- Chitosan/Lignosulfonate Nanospheres as "Green" Biocide for Controlling the Microbiologically Influenced Corrosion of Carbon Steel.Materials (Basel, Switzerland) · 2020Article
- The Antimicrobial Properties of Chitosan Can be Tailored by Formulation.Marine drugs · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaginal infections are associated with high recurrence, which is often due to a lack of efficient treatment of complex vaginal infections comprised of several types of pathogens, especially fungi and bacteria. Chitosan, a mucoadhesive polymer with known antifungal effect, could offer a great improvement in vaginal therapy; the chitosan-based nanosystem could both provide antifungal effects and simultaneously deliver antibacterial drugs. We prepared chitosan-containing liposomes, chitosomes, where chitosan is both embedded in liposomes and surface-available as a coating layer. For antimicrobial activity, we entrapped metronidazole as a model drug. To prove that mucoadhesivness alone is not sufficient for successful delivery, we used Carbopol-containing liposomes as a control. All vesicles were characterized for their size, zeta potential, entrapment efficiency, and in vitro drug release. Chitosan-containing liposomes were able to assure the prolonged release of metronidazole. Their antifungal activity was evaluated in a
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.