Evidence map›Paper›PMID 28273445›Full record

ArticleStructure (London, England : 1993)2017

Predicting Allosteric Changes from Conformational Ensembles.

Martin Zacharias

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Protein Multiple Conformation Prediction Using Multi-Objective Evolution Algorithm.Interdisciplinary sciences, computational life sciences · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Martin ZachariasPhysics Department T38, Technical University of Munich, James-Franck-Straße 1, 85748 Garching, Germany; Center for Integrated Protein Science, 81377 Munich, Germany. Electronic address: martin.zacharias@mytum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Structure, Greener et al. (2017) describe a new computational approach to generate conformational ensembles of proteins based on two experimental input structures. The method shows promise for rapidly predicting global protein flexibility and for the identification of putative binding sites for allosteric effectors on proteins.

Indexed as

Allosteric RegulationBinding SitesComputational BiologyMolecular Dynamics SimulationProtein ConformationProteinsProteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.