Evidence map›Paper›PMID 28273361›Full record

ArticleClinical cardiology2017

Transcatheter aortic valve implantation improves carotid and vertebral arterial blood flow in patients with severe aortic stenosis: practical role of orthostatic stress test.

Pawel Kleczyński, Pawel Petkow Dimitrow, Artur Dziewierz, Andrzej Surdacki, Dariusz Dudek

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pawel KleczyńskiDepartment of Cardiology, Institute of Cardiology, Jagiellonian University, Krakow, Poland.
Pawel Petkow DimitrowDepartment of Cardiology, Institute of Cardiology, Jagiellonian University, Krakow, Poland.
Artur DziewierzDepartment of Cardiology, Institute of Cardiology, Jagiellonian University, Krakow, Poland.
Andrzej SurdackiDepartment of Cardiology, Institute of Cardiology, Jagiellonian University, Krakow, Poland.
Dariusz DudekDepartment of Cardiology, Institute of Cardiology, Jagiellonian University, Krakow, Poland.
Jagiellonian University · PLInstitute of Cardiology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are no data on the impact of transcatheter aortic valve implantation (TAVI) on carotid and vertebral arterial blood flow. Our aim was to assess the effects of the orthostatic stress test on carotid and vertebral artery blood flow in patients with severe aortic stenosis (AS) undergoing TAVI. HYPOTHESIS: TAVI may have beneficial effect on carotid and vertebral artery flow in patients with severe aortic stenosis.

methodsThirty carefully selected patients with severe AS undergoing TAVI were enrolled. Peak systolic blood-flow velocity and end-diastolic velocity in the common carotid artery, internal carotid artery, and vertebral artery, as well as spectral analysis of flow pattern with time-averaged maximum velocity (centimeters per second), time-averaged mean velocity (centimeters per second), and flow volume (milliliters per minute) on both sides were measured by duplex ultrasound. Measurements were performed in the supine position and at 1 to 2 minutes after the assumption of the standing position at baseline and 3 months after TAVI.

resultsAll duplex ultrasound parameters assessed in the supine position have significantly improved in patients after TAVI as compared to baseline (P < 0.001 for all). The orthostatic stress test induced decrease of carotid and vertebral arterial flow velocities in AS patients before and after TAVI. However, the drop in velocities and flow volume was numerically lower after TAVI.

conclusionsTAVI may have some beneficial effect on extracranial artery blood flow by minimalization of its decrease as a response to orthostatic stress.

Indexed as

AgedAged, 80 and overAortic Valve StenosisBlood Flow VelocityCardiac CatheterizationCarotid ArteriesEchocardiographyExercise TestFemaleHumansMaleSeverity of Illness IndexStroke VolumeSystoleTranscatheter Aortic Valve ReplacementUltrasonography, Doppler, Duplexaortic stenosiscerebral blood flowDoppler ultrasoundorthostatic stresstranscatheter aortic valve implantation

Identifiers

PMID28273361
PMCPMC6490572
OpenAlexW2593627387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.