Evidence map›Paper›PMID 28273094›Full record

ArticlePloS one2017

Spirometry, questionnaire and electronic medical record based COPD in a population survey: Comparing prevalence, level of agreement and associations with potential risk factors.

Floor Borlée, C Joris Yzermans, Esmeralda Krop, Bernadette Aalders, Jos Rooijackers, Jan-Paul Zock, Christel E van Dijk, Catharina B M Maassen, François Schellevis, Dick Heederik and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Clarifying Chronic Obstructive Pulmonary Disease Genetic Associations Observed in Biobanks via Mediation Analysis of Smoking.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
  6. Lung function in Lolland-Falster Health Study (LOFUS).The clinical respiratory journal · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Trait Insights Gained by Comparing Genome-Wide Association Study Results using Different Chronic Obstructive Pulmonary Disease Definitions.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Floor BorléeInstitute for Risk Assessment Sciences, IRAS, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-3297-4403
C Joris YzermansNetherlands Institute for Health Services Research, NIVEL, Utrecht, The Netherlands.
Esmeralda KropInstitute for Risk Assessment Sciences, IRAS, Utrecht University, Utrecht, The Netherlands.
Bernadette AaldersNetherlands Expertise Centre for Occupational Respiratory Disorders, Utrecht, The Netherlands.
Jos RooijackersNetherlands Expertise Centre for Occupational Respiratory Disorders, Utrecht, The Netherlands.
Jan-Paul ZockNetherlands Institute for Health Services Research, NIVEL, Utrecht, The Netherlands.
Christel E van DijkNetherlands Institute for Health Services Research, NIVEL, Utrecht, The Netherlands.
Catharina B M MaassenNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control, Bilthoven, The Netherlands.
François SchellevisNetherlands Institute for Health Services Research, NIVEL, Utrecht, The Netherlands.
Dick HeederikInstitute for Risk Assessment Sciences, IRAS, Utrecht University, Utrecht, The Netherlands.
Lidwien A M SmitInstitute for Risk Assessment Sciences, IRAS, Utrecht University, Utrecht, The Netherlands.
Netherlands Institute for Health Services Research · NLUtrecht University · NLNetherlands Center for Occupational Diseases · NLNational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOPD-diagnosis is confirmed by post-bronchodilator (BD) spirometry. However, epidemiological studies often rely on pre-BD spirometry, self-reports, or medical records. This population-based study aims to determine COPD-prevalence based on four different operational definitions and their level of agreement, and to compare associations between COPD-definitions and risk factors.

methodsCOPD-prevalence in 1,793 adults from the general Dutch population (aged 18-70 years) was assessed based on self-reported data, Electronic Medical Records (EMR), and post-BD spirometry: using the FEV1/FVC below the lower limit of normal (LLN) and GOLD fixed cut-off (FEV1/FVC <0.70). Using spirometry as a reference, sensitivity was calculated for self-reported and EMR-based COPD. Associations between COPD and known risk factors were assessed with logistic regression. Data were collected as part of the cross-sectional VGO study (Livestock Farming and Neighboring Residents' Health Study).

resultsThe highest prevalence was found based on spirometry (GOLD: 10.9%, LLN: 5.9%), followed by self-report (4.6%) and EMR (2.9%). Self-reported or EMR-based COPD identified less than 30% of all COPD-cases based on spirometry. The direction of association between known risk factors and COPD was similar across the four definitions, however, magnitude and significance varied. Especially indicators of allergy were more strongly associated with self-reported COPD compared to the other definitions.

conclusionsCOPD-prevalence varied depending on the used definition. A substantial number of subjects with spirometry-based COPD cannot be identified with questionnaires or medical records which can cause underestimation of COPD-prevalence. The influence of the different COPD-definitions on associations with known risk factors was limited.

Indexed as

SpirometryAdultAgedCross-Sectional StudiesElectronic Health RecordsFemaleForced Expiratory VolumeHumansMaleMiddle AgedOdds RatioPredictive Value of TestsPrevalencePulmonary Disease, Chronic ObstructiveRisk FactorsSelf Report

Identifiers

PMID28273094
PMCPMC5342260
OpenAlexW2594672107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.