Evidence map›Paper›PMID 28272772›Full record

ReviewJournal of cellular and molecular medicine2017

TUSC3: a novel tumour suppressor gene and its functional implications.

Xinshuang Yu, Chunjuan Zhai, Yujun Fan, Jiandong Zhang, Ning Liang, Fengjun Liu, Lili Cao, Jia Wang, Juan Du

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

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  16. Platelets and Defective N-Glycosylation.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Xinshuang YuDepartment of Radiation Oncology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Chunjuan ZhaiDepartment of Cardiology, Shandong Provincial Hospital affiliated to Shandong University, Shandong University, Jinan, China.
Yujun FanMedical Management Service Center of Shandong Provincial Health and Family Planning Commission, Jinan, China.
Jiandong ZhangDepartment of Radiation Oncology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Ning LiangDepartment of Radiation Oncology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Fengjun LiuDepartment of Radiation Oncology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Lili CaoMedical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Jia WangChina Institute of Veterinary Drugs Control, Beijing, China.
Juan DuDepartment of Radiation Oncology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Shandong University · CNShandong Provincial QianFoShan Hospital · CNChina Institute of Veterinary Drug Control · CNShandong Province Health and Family Planning Commission · CNShandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N-glycosylation of nascent proteins. Known to be related to autosomal recessive mental retardation for several years, TUSC3 has only recently been identified as a potential tumour suppressor gene. Based on the structure and function of TUSC3, specific mechanisms in various diseases have been investigated. Several studies have demonstrated that TUSC3 is an Mg

Indexed as

Genes, Tumor SuppressorAnimalsDiseaseEmbryonic DevelopmentEpigenesis, GeneticHumansMembrane ProteinsMutationMembrane ProteinsN-glycosylation reactionoligosaccharyl transferasetumourgenesistumour suppressor candidate 3

Identifiers

PMID28272772
PMCPMC5571513
OpenAlexW2594478633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.