Evidence map›Paper›PMID 28272357›Full record

ReviewMolecules (Basel, Switzerland)2017

Implications of Resveratrol on Glucose Uptake and Metabolism.

David León, Elena Uribe, Angara Zambrano, Mónica Salas

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.Cardiovascular & hematological disorders drug targets · 2026
    Pooled it
  2. Article
  3. Review
  4. Plant extract fromHeliyon · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Dietary polyphenols in lipid metabolism: A role of gut microbiome.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2020
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Special Issue: Improvements for Resveratrol Efficacy.Molecules (Basel, Switzerland) · 2017
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David LeónInstituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 509000, Chile. davidleonn90@gmail.com.
Elena UribeDepartamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4030000, Chile. auribe@udec.cl.
Angara ZambranoInstituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 509000, Chile. angara.zambrano@uach.cl.
Mónica SalasInstituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 509000, Chile. monicasalas@uach.cl.
Austral University of Chile · CLUniversity of Concepción · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol-a polyphenol of natural origin-has been the object of massive research in the past decade because of its potential use in cancer therapy. However, resveratrol has shown an extensive range of cellular targets and effects, which hinders the use of the molecule for medical applications including cancer and type 2 diabetes. Here, we review the latest advances in understanding how resveratrol modulates glucose uptake, regulates cellular metabolism, and how this may be useful to improve current therapies. We discuss challenges and findings regarding the inhibition of glucose uptake by resveratrol and other polyphenols of similar chemical structure. We review alternatives that can be exploited to improve cancer therapies, including the use of other polyphenols, or the combination of resveratrol with other molecules and their impact on glucose homeostasis in cancer and diabetes.

Indexed as

AnimalsAntineoplastic Agents, PhytogenicBiological TransportCarbohydrate MetabolismDiabetes Mellitus, Type 2Drug SynergismGlucoseHomeostasisHumansNeoplasmsPolyphenolsResveratrolSignal TransductionStilbenesAntineoplastic Agents, PhytogenicGlucosePolyphenolsResveratrolStilbenescancerdiabetesglucose transport and metabolismpolyphenolsresveratrolsignal transduction

Identifiers

PMID28272357
PMCPMC6155386
OpenAlexW2593128242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.