Evidence map›Paper›PMID 28272355›Full record

ArticleInternational journal of molecular sciences2017

Serum-Infliximab Trough Levels in 45 Children with Inflammatory Bowel Disease on  Maintenance Treatment.

Helena Rolandsdotter, Per Marits, Ulf Sundin, Ann-Charlotte Wikström, Ulrika L Fagerberg, Yigael Finkel, Michael Eberhardson

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Helena RolandsdotterDepartment of Gastroenterology, Sachs' Children and Youth Hospital, SE-11883 Stockholm, Sweden. helena.jonsson.rolandsdotter@ki.se.
Per MaritsDepartment of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, SE-17776 Stockholm, Sweden. per.marits@sll.se.
Ulf SundinDepartment of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, SE-17776 Stockholm, Sweden. ulf.sundin.49@gmail.com.
Ann-Charlotte WikströmDepartment of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, SE-17776 Stockholm, Sweden. ann-charlotte.wikstrom@sll.se.
Ulrika L FagerbergDepartment of Women's and Children's Health, Karolinska Institute, SE-11776 Stockholm, Sweden. ulrika.fagerberg@regionvastmanland.se.
Yigael FinkelDepartment of Gastroenterology, Sachs' Children and Youth Hospital, SE-11883 Stockholm, Sweden. yigael.finkel@ki.se.
Michael EberhardsonDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institute, SE-11883 Stockholm, Sweden. michael.eberhardson@ki.se.
Karolinska University Hospital · SEKarolinska Institutet · SEDanderyds sjukhus · SEStockholm South General Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of trough serum infliximab (s-IFX) and antibodies toward IFX (ATI) during maintenance treatment remains unclear in children. The aim of the present study was to investigate trough s-IFX and ATI to identify any correlation with inflammatory activity and clinical response in a pediatric inflammatory bowel disease (IBD) cohort. We investigated the s-IFX trough levels in pediatric IBD patients (

Indexed as

AdolescentAnti-Inflammatory Agents, Non-SteroidalChildChild, PreschoolDrug MonitoringFemaleHumansInfantInflammatory Bowel DiseasesInfliximabMaleTreatment OutcomeAnti-Inflammatory Agents, Non-SteroidalInfliximabantibodies toward infliximabCrohn’s diseaseinflammatory bowel diseasetrough levelsulcerative colitis

Identifiers

PMID28272355
PMCPMC5372591
OpenAlexW2591923568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.