Evidence map›Paper›PMID 28272306›Full record

ArticleInternational journal of molecular sciences2017

AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia.

Shuai Yang, Xinmei Zhao, Hui Xu, Fan Chen, Yitao Xu, Zhe Li, Daniel Sanchis, Liang Jin, Yubin Zhang, Junmei Ye

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. In Vivo Evaluation ofNutrients · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Phytoceuticals in Acute Pancreatitis: Targeting the Balance between Apoptosis and Necrosis.Evidence-based complementary and alternative medicine : eCAM · 2018
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Shuai YangState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. yangshuai923@163.com.
Xinmei ZhaoState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. 14211030585@cpu.edu.cn.
Hui XuCenter of Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing 210093, China. hxu@diacarta.com.
Fan ChenState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. fancy0703@163.com.
Yitao XuState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. yito-xu@outlook.com.
Zhe LiDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China. zhelizl@gmail.com.
Daniel SanchisInstitut de Recerca Biomèdica de Lleida (IRBLLEIDA)-Universitat de Lleida, Edifici Biomedicina-I. Av. Rovira Roure, 80., 25198 Lleida, Spain. daniel.sanchis@cmb.udl.cat.
Liang JinState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. liangjin1975@cpu.edu.cn.
Yubin ZhangState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. ybzhang@cpu.edu.cn.
Junmei YeState Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. junmeiye@cpu.edu.cn.
China Pharmaceutical University · CNBiomedical Research Institute of Lleida · ESNanjing University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AKT (protein kinase B, PKB) family has been shown to participate in diverse cellular processes, including apoptosis. Previous studies demonstrated that protein kinase B2 (AKT2

Indexed as

ApoptosisActive Transport, Cell NucleusAnimalsApoptosis Inducing FactorCaspasesCell HypoxiaCell NucleusCells, CulturedCytochromes cDNA FragmentationEndodeoxyribonucleasesHEK293 CellsHumansMiceMitochondria, HeartMyocardial IschemiaApoptosis Inducing FactorCaspasesCytochromes cEndodeoxyribonucleasesendonuclease GProto-Oncogene Proteins c-aktapoptosisapoptosis-inducing factor (AIF)cardiomyocytesendonuclease G (EndoG)ischemiaprotein kinase B2 (AKT2)

Identifiers

PMID28272306
PMCPMC5372581
OpenAlexW2591853526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.