Evidence map›Paper›PMID 28271845›Full record

ReviewLancet (London, England)2017

Syndemics and the biosocial conception of health.

Merrill Singer, Nicola Bulled, Bayla Ostrach, Emily Mendenhall

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Lancet (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04646408 (Determinants of Cardiovascular Disease, Kidney Disease and Diabetes in People of African Ancestry With HIV), which is not on this map. Cited by 668 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
668citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04646408 unknown statusnot on this mapstarted 2020, after this paper: background citation

Determinants of Cardiovascular Disease, Kidney Disease and Diabetes in People of African Ancestry With HIV (CKD Study)

TypeobservationalSponsorKing's College Hospital NHS TrustRan2020 to 2022Enrolled400ConditionsCardiovascular Diseases, Diabetes Mellitus, Chronic Kidney Diseases
3 · Its place in the literature

Who cites it

668 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  10. Plant-based and sustainable diet: A systematic review of its impact on obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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608 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Merrill SingerDepartment of Anthropology, University of Connecticut, Storrs, CT, USA; Department of Community Medicine, University of Connecticut, Storrs, CT, USA. Electronic address: Merrill.Singer@uconn.edu.
Nicola BulledDivision of Interdisciplinary & Global Studies, Worcester Polytechnic Institute, Worcester, MA, USA.
Bayla OstrachBoston University School of Medicine, Boston, MA, USA.
Emily MendenhallSchool of Foreign Service, Georgetown University, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The syndemics model of health focuses on the biosocial complex, which consists of interacting, co-present, or sequential diseases and the social and environmental factors that promote and enhance the negative effects of disease interaction. This emergent approach to health conception and clinical practice reconfigures conventional historical understanding of diseases as distinct entities in nature, separate from other diseases and independent of the social contexts in which they are found. Rather, all of these factors tend to interact synergistically in various and consequential ways, having a substantial impact on the health of individuals and whole populations. Specifically, a syndemics approach examines why certain diseases cluster (ie, multiple diseases affecting individuals and groups); the pathways through which they interact biologically in individuals and within populations, and thereby multiply their overall disease burden, and the ways in which social environments, especially conditions of social inequality and injustice, contribute to disease clustering and interaction as well as to vulnerability. In this Series, the contributions of the syndemics approach for understanding both interacting chronic diseases in social context, and the implications of a syndemics orientation to the issue of health rights, are examined.

Indexed as

Social EnvironmentCoinfectionHumansMental HealthMultiple Chronic ConditionsNoncommunicable DiseasesPovertyRisk FactorsSyndromeVulnerable Populations

Identifiers

PMID28271845

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.