Evidence map›Paper›PMID 28271469›Full record

ReviewProbiotics and antimicrobial proteins2017

Lactobacillus plantarum and Its Probiotic and Food Potentialities.

Hamza Ait Seddik, Farida Bendali, Frédérique Gancel, Ismail Fliss, Giuseppe Spano, Djamel Drider

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 190 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
190citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05194033 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination: A Prospective, Randomized, Double-blind, Placebo-Controlled Trial (Trial 1)

TypeinterventionalSponsorPeking UniversityRan2022 to 2022Enrolled31ConditionsSARS-CoV-2ArmsProbiotics daily, Placebo daily
NCT05195047 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination: A Prospective, Randomized, Double-blind, Placebo-Controlled Trial (Trial 2)

TypeinterventionalSponsorPeking UniversityRan2022 to 2022Enrolled44ConditionsSARS-CoV-2Arms1 week placebo(Week 1), 1 week of probiotics(Week 1), 1 week placebo(Week 2), 1 week of probiotics(Week 2), 1 week placebo(Week 3)
3 · Its place in the literature

Who cites it

190 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Synthetic and systems biotechnology · 2027
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Evaluation ofMicroorganisms · 2026
    Article
  13. Article
  14. Impact of DietaryAnimals : an open access journal from MDPI · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Dietary supplementation withFrontiers in microbiology · 2026
    Article
  19. Review
  20. Article

130 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamza Ait SeddikUniv. Lille, INRA, Univ. Artois, Univ. Littoral Côte d'Opale, EA 7394 - ICV - Institut Charles Viollette, F-59000, Lille, France.
Farida BendaliLaboratoire de Microbiologie Appliquée, Faculté des Sciences de la Nature et de la Vie de l'Université de Bejaia, 06000, Bejaia, Algeria.
Frédérique GancelUniv. Lille, INRA, Univ. Artois, Univ. Littoral Côte d'Opale, EA 7394 - ICV - Institut Charles Viollette, F-59000, Lille, France.
Ismail FlissSTELA Dairy Research Center, Nutrition and Functional Foods Institute, Université Laval, Québec, QC, Canada.
Giuseppe SpanoDepartment of Science of Agriculture, Food and Environment, University of Foggia, Foggia, Italy.
Djamel DriderUniv. Lille, INRA, Univ. Artois, Univ. Littoral Côte d'Opale, EA 7394 - ICV - Institut Charles Viollette, F-59000, Lille, France. djamel.drider@univ-lille1.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of studies claiming probiotic health effects of Lactobacillus plantarum is escalating. Lb. plantarum is a lactic acid bacterium found in diverse ecological niches, highlighting its particular capabilities of adaptation and genome plasticity. Another function that needs to be underlined is the capabilities of Lb. plantarum to produce diverse and potent bacteriocins, which are antimicrobial peptides with possible applications as food preservative or antibiotic complementary agents. Taken together, all these characteristics design Lb. plantarum as a genuine model for academic research and viable biological agent with promising applications. The present review aims at shedding light on the safety of Lb. plantarum and run through the main studies underpinning its beneficial claims. The mechanisms explaining probiotic-related features are discussed.

Indexed as

AnimalsAnti-Bacterial AgentsFood MicrobiologyFood PreservationFood PreservativesHumansLactiplantibacillus plantarumProbioticsAnti-Bacterial AgentsFood PreservativesLactic acid bacteriaLb. plantarumLb. plantarum genomeProbiotic safety

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.