Evidence map›Paper›PMID 28271366›Full record

ReviewMolecular imaging and biology2017

Advancing Immune and Cell-Based Therapies Through Imaging.

Vladimir Ponomarev

Abstract readReview
In one paragraph

Review in Molecular imaging and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  3. Immune PET Imaging.Radiologic clinics of North America · 2021
    Review
  4. Development of [European journal of nuclear medicine and molecular imaging · 2021
    Article
  5. Predicting CAR-T cell Immunotherapy Success through ImmunoPET.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. [Basis of Tumor Microenvironment Relevant to Immunotherapies for Brain Metastases of NSCLC].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2019
    Review
  10. Imaging of CAR T-Cells in Cancer Patients: Paving the Way to Treatment Monitoring and Outcome Prediction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  11. In Vivo PET Tracking ofMolecular therapy : the journal of the American Society of Gene Therapy · 2019
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Vladimir PonomarevDepartment of Radiology, Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Ave Z-2063, Box 501, New York, NY, 10065, USA. ponomarv@mskcc.org.ORCID 0000-0002-9119-9128

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapies include various approaches, ranging from stimulating effector mechanisms to counteracting inhibitory and suppressive mechanisms, and creating a forum for discussing the most effective means of advancing these therapies through imaging is the focus of the newly formed Imaging in Cellular and Immune Therapies (ICIT) interest group within the World Molecular Imaging Society. Efforts are being made in the identification and validation of predictive biomarkers for a number of immunotherapies. Without predictive biomarkers, a considerable number of patients may receive treatments that have no chance of offering a benefit. This will reflect poorly on the field of immunotherapy and will yield false hopes in patients while at the same time contributing to significant cost to the healthcare system. This review summarizes the main strategies in cancer immune and cell-based therapies and discusses recent advances in imaging strategies aimed to improve cancer immunotherapy outcomes.

Indexed as

AnimalsBiomarkersHumansImmunotherapyLeukocytesMolecular ImagingOutcome Assessment, Health CareBiomarkersCell-based therapyImagingImmunotherapy

Identifiers

PMID28271366
PMCPMC5406436

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.