Evidence map›Paper›PMID 28271311›Full record

Trial reportEuropean journal of applied physiology2017

Soft tissues, areal bone mineral density and hip geometry estimates in active young boys: the PRO-BONE study.

Kelly Wilkinson, Dimitris Vlachopoulos, Panagiota Klentrou, Esther Ubago-Guisado, Augusto César Ferreira De Moraes, Alan R Barker, Craig A Williams, Luis A Moreno, Luis Gracia-Marco

Open access · hybridAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Mediterranean diet, diet quality, and bone mineral content in adolescents: the HELENA study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Kelly WilkinsonChildren's Health and Exercise Research Centre, Sport and Health Sciences, St. Luke's Campus, University of Exeter, Exeter, EX1 2LU, UK.
Dimitris VlachopoulosChildren's Health and Exercise Research Centre, Sport and Health Sciences, St. Luke's Campus, University of Exeter, Exeter, EX1 2LU, UK.
Panagiota KlentrouDepartment of Kinesiology, Brock University, St. Catharines, Ontario, Canada.
Esther Ubago-GuisadoIGOID Research Group, University of Castilla-La Mancha, Toledo, Spain.
Augusto César Ferreira De MoraesYCARE (Youth/Child cArdiovascular Risk and Environmental) Research Group, University of São Paulo, School of Medicine, São Paulo, São Paulo, Brazil.
Alan R BarkerChildren's Health and Exercise Research Centre, Sport and Health Sciences, St. Luke's Campus, University of Exeter, Exeter, EX1 2LU, UK.
Craig A WilliamsChildren's Health and Exercise Research Centre, Sport and Health Sciences, St. Luke's Campus, University of Exeter, Exeter, EX1 2LU, UK.
Luis A MorenoGrowth, Exercise, Nutrition and Development Research Group, University of Zaragoza, Zaragoza, Spain.
Luis Gracia-MarcoChildren's Health and Exercise Research Centre, Sport and Health Sciences, St. Luke's Campus, University of Exeter, Exeter, EX1 2LU, UK. L.A.Gracia-Marco@exeter.ac.uk.
University of Exeter · GBUniversidad de Zaragoza · ESBrock University · CAUniversity of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSoft tissues, such as fat mass (FM) and lean mass (LM), play an important role in bone development but this is poorly understood in highly active youths. The objective of this study was to determine whether FM or LM is a stronger predictor of areal bone mineral density (aBMD) and hip geometry estimates in a group of physically active boys after adjusting for height, chronological age, moderate-to-vigorous physical activity (MVPA), FM, and LM.

methodsParticipants included 121 boys (13.1 ± 1.0 years) from the PRO-BONE study. Bone mineral content (BMC) and aBMD were measured at total body, femoral neck and lumbar spine using dual-energy X-ray absorptiometry (DXA), and hip structural analysis was used to estimate bone geometry at the femoral neck. Body composition was assessed using DXA. The relationships of FM and LM with bone outcomes were analysed using simple and multiple linear regression analyses.

resultsPearson correlation coefficients showed that total body (less head) aBMD was significantly correlated with LM but not FM. Multiple linear regression analyses showed that FM, after accounting for height, age, MVPA and LM had no significant relationship with aBMD or hip geometry estimates, except for arms aBMD. By contrast, there were positive associations between LM and most aBMD and hip geometry estimates, after accounting height, age, MVPA and FM.

conclusionsThe results of this study suggest that LM, and not FM, is the stronger predictor of aBMD and hip geometry estimates in physically active boys.

trial registrationClinicalTrials.gov ISRCTN17982776.

Indexed as

Bone DensityExerciseAdipose TissueAdolescentChildFemurHumansMaleMuscle, SkeletalAdolescentsBody compositionBone healthFat massHip structural analysisLean mass

Identifiers

PMID28271311
OpenAlexW2593644018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.