ReviewDrugs2017
Pediatric Osteoporosis: Diagnosis and Treatment Considerations.
Review in Drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Bisphosphonate treatment for secondary osteoporosis in children, youth, and young adults: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Pooled it
- Medication-Related Impacts on Pediatric Bone Health.Journal of the Pediatric Orthopaedic Society of North America · 2025Review
- Orthodontics in Pediatric Osteoporosis: A Narrative Literature Review.Children (Basel, Switzerland) · 2025Review
- Sonographic cortical bone thickness measurement: can it predict bone mineral density in the pediatric population?Diagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Diagnosis and Management of Osteoporosis in Children and Adolescents.Ewha medical journal · 2023Review
- Osteoporosis in children and adolescents: when to suspect and how to diagnose it.European journal of pediatrics · 2022Review
- Drug Treatment of Low Bone Mass and Other Bone Conditions in Pediatric Patients.Paediatric drugs · 2022Review
- Correlation between vitamin D levels and bone metabolism in children with cow's milk allergy.The Journal of international medical research · 2022Article
- Efficacy and safety of bisphosphonates on childhood osteoporosis secondary to chronic illness or its treatment: a meta-analysis.Therapeutic advances in chronic disease · 2022Article
- Cellular senescence in musculoskeletal homeostasis, diseases, and regeneration.Bone research · 2021Review
- Efficacy and safety of intravenous pamidronate infusion for treating osteoporosis in children and adolescents.Annals of pediatric endocrinology & metabolism · 2021Article
- Expert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children.Pediatric rheumatology online journal · 2020Article
- Non-osteogenic muscle hypertrophy in children with McArdle disease.Journal of inherited metabolic disease · 2018Article
- Can radial bone mineral density predict spinal bone mineral density in patients with advanced Duchenne muscular dystrophy?Medicine · 2018Article
- Dental Manifestations of Pediatric Bone Disorders.Current osteoporosis reports · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporosis is now increasingly recognized in children due to the increased prevalence of disorders associated with bone loss. Fragility fractures represent the cardinal clinical features of pediatric osteoporosis and children presenting with fragility fractures deserve an accurate assessment to rule out a secondary cause. Indeed, in the pediatric population, a low bone mass is often a consequence of a chronic disease or its treatment; genetic bone disorders represent the cause of only a small fraction of cases. The position statement of the International Society for Clinical Densitometry guides physicians in interpreting densitometric data and making diagnoses of osteoporosis in children. Once a diagnosis of osteoporosis has been made, the aim is to identify children in whom bone status may deteriorate if left untreated. To date, bisphosphonates have represented the mainstay of treatment for pediatric osteoporosis. However, due to the peculiar pathophysiology of osteoporosis in this age group, a pharmacological agent with an anabolic effect on bone may provide clinicians with other therapeutic options in children. Multicenter studies are needed to optimize treatments and define optimal clinical response in treated children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.