Evidence map›Paper›PMID 28271001›Full record

ArticleBiomedical optics express2017

Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging.

Yan Li, Joseph Jing, Yueqiao Qu, Yusi Miao, Buyun Zhang, Teng Ma, Mingyue Yu, Qifa Zhou, Zhongping Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  16. Quadruple ultrasound, photoacoustic, optical coherence, and fluorescence fusion imaging with a transparent ultrasound transducer.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan LiDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA.
Joseph JingDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA.
Yueqiao QuDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA.
Yusi MiaoDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA.
Buyun ZhangDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA.
Teng MaThe Resource Center for Medical Ultrasonic Transducer Technology, University of Southern California, Los Angeles 90089, USA.
Mingyue YuThe Resource Center for Medical Ultrasonic Transducer Technology, University of Southern California, Los Angeles 90089, USA.
Qifa ZhouThe Resource Center for Medical Ultrasonic Transducer Technology, University of Southern California, Los Angeles 90089, USA.
Zhongping ChenDepartment of Biomedical Engineering and Beckman laser institute, University of California, Irvine, Irvine, CA 92617, USA; Department of Biomedical Engineering, University of California, 5200 Engineering Hall, Irvine, California 92697, USA.

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
Phase resolved ARF optical coherence elastography for intravascular imagingR01HL125084 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ZHOU, QIFA · 2014 to 2023
$5.6M
Combined OCT/US/PAT system for intravascular ImagingR01HL127271 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, PATEL, PRANAV · 2015 to 2018
$2.7M
High Resolution Elastograpy of Retina Under Prosthetic Electrical StimulationR01EY026091 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, ZHOU, QIFA · 2016 to 2019
$2.0M
Training Program in Cardiovascular Applied Research and EntrepreneurshipT32HL116270 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUGHES, CHRISTOPHER C. W. · 2013 to 2022
$1.6M
Elastographic Imaging of the Retina/Choroid in Age-Related Macular DegenerationR01EY021529 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHEN, ZHONGPING, SILVERMAN, RONALD H · 2012 to 2015
$1.4M
NEI NIH HHS R01 EY021529NEI NIH HHS R01 EY026091NHLBI NIH HHS R01 HL125084NHLBI NIH HHS R01 HL127271NHLBI NIH HHS T32 HL116270NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

We present a tri-modality imaging system and fully integrated tri-modality probe for intravascular imaging. The tri-modality imaging system is able to simultaneously acquire optical coherence tomography (OCT), ultrasound (US), and fluorescence imaging. Moreover, for fluorescence imaging, we used the FDA-approved indocyanine green (ICG) dye as the contrast agent to target lipid-loaded macrophages. We conducted imaging from a male New Zealand white rabbit to evaluate the performance of the tri-modality system. In addition, tri-modality images of rabbit aortas were correlated with hematoxylin and eosin (H&E) histology to check the measurement accuracy. The fully integrated miniature tri-modality probe, together with the use of ICG dye suggest that the system is of great potential for providing a more accurate assessment of vulnerable plaques in clinical applications.

Indexed as

(110.4190) Multiple imaging(110.4500) Optical coherence tomography(110.7170) Ultrasound(170.0170) Medical optics and biotechnology(170.2150) Endoscopic imaging(260.2510) Fluorescence

Identifiers

PMID28271001
PMCPMC5330557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.