ArticleBiomedical optics express2017
Hematocrit dependence of flow signal in optical coherence tomography angiography.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Correlation analysis of physical fitness and retinal microvasculature by OCT angiography in healthy adults.PloS one · 2019Trial
- Optical coherence tomography angiography reveals structural and hemodynamic remodeling of cerebral penetrating vessels owing to aging.Biomedical optics express · 2026Article
- Repeatability and reliability of retinal arterial hemodynamics measurement using Doppler holography.Journal of biomedical optics · 2026Article
- Quantitative evaluation of the topographical maps of three-dimensional choroidal vascularity index in gestational diabetes mellitus: a cross-sectional observational study.BMC pregnancy and childbirth · 2026Observational
- Widefield OCT angiography.Progress in retinal and eye research · 2025Review
- Retinal vessel density and cognitive function in healthy older adults.Experimental brain research · 2025Article
- Impact of preocular and ocular circulatory dynamics on the vascular density of retinal capillary plexuses and choriocapillaris.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Observational
- Light conditions influence optic nerve OCT angiography parameter in healthy subjects with neutral pupils.Scientific reports · 2023Article
- Dynamic inverse SNR-decorrelation OCT angiography with GPU acceleration.Biomedical optics express · 2022Article
- OCTA Derived Vessel Skeleton Density Versus Flux and Their Associations With Systemic Determinants of Health.Investigative ophthalmology & visual science · 2022Article
- Commentary: Effect of exercise on ocular blood flow.Indian journal of ophthalmology · 2021Article
- Evaluation of the effect of high-intensity interval training on macular microcirculation via swept-source optical coherence tomography angiography in young football players.Indian journal of ophthalmology · 2021Article
- Evaluating Retinal and Choroidal Perfusion Changes after Isometric and Dynamic Activity Using Optical Coherence Tomography Angiography.Diagnostics (Basel, Switzerland) · 2021Article
- [Optical coherence tomography angiography as a future diagnostic tool in sports medicine?]Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019Review
- Enhanced Quantification of Retinal Perfusion by Improved Discrimination of Blood Flow From Bulk Motion Signal in OCTA.Translational vision science & technology · 2018Article
- Polarization-multiplexed, dual-beam swept source optical coherence tomography angiography.Journal of biophotonics · 2018Article
- Extended axial imaging range, widefield swept source optical coherence tomography angiography.Journal of biophotonics · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The hematocrit dependence of flow signal (split-spectrum amplitude decorrelation angiography-SSADA decorrelation value) was investigated in this paper. Based on the normalized field temporal correlation function and concentration dependent particle scattering properties, the relationship between hematocrit and flow signal was analytically derived. Experimental verification of the relationship was performed with custom-designed microfluidic chips and human blood with 45%, 40% and 32% hematocrit. It was found that, in large flow channels and blood vessels, the normal hematocrit is near the decorrelation saturation point and therefore a change in hematocrit has little effect on the SSADA decorrelation value (flow signal). However, in narrow channels in the capillary size range, the effective hematocrit (adjusted for the overlap between OCT beam and channel) is in the range of 6.7-9.5% and therefore variation in hematocrit does significantly affect the flow signal.
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Registered trials
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