Evidence map›Paper›PMID 28270981›Full record

ArticleBiomedical optics express2017

Label-free imaging of amyloids using their intrinsic linear and nonlinear optical properties.

Patrik K Johansson, Patrick Koelsch

Abstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Crystallization of L-Cysteine in Heavy Water Induces Intrinsic Fluorescence.Angewandte Chemie (International ed. in English) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Amyloid Fibrils of Stefin B Show Anisotropic Properties.International journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
  11. One- and Two-Photon Excited Autofluorescence of Lysozyme Amyloids.The journal of physical chemistry letters · 2022
    Article
  12. Article
  13. Review
  14. Plasmonic Amyloid Tactoids.Advanced materials (Deerfield Beach, Fla.) · 2021
    Article
  15. Fluorescence Emission of Self-assembling Amyloid-like Peptides: Solution versus Solid State.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrik K JohanssonNational ESCA Surface Analysis Center for Biomedical Problems, Department of Bioengineering, University of Washington, 4000 15th Ave NE, Seattle, WA 98195, USA.
Patrick KoelschNational ESCA Surface Analysis Center for Biomedical Problems, Department of Bioengineering, University of Washington, 4000 15th Ave NE, Seattle, WA 98195, USA.

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G, GAMBLE, LARA · 2003 to 2019
$17.6M
NIBIB NIH HHS P41 EB002027
6 · The paper itself

Abstract

The optical properties of amyloid fibers are often distinct from those of the source protein in its non-fibrillar form. These differences can be utilized for label-free imaging or characterization of such structures, which is particularly important for understanding amyloid fiber related diseases such as Alzheimer's and Parkinson's disease. We demonstrate that two amyloid forming proteins, insulin and

Indexed as

(160.2540) Fluorescent and luminescent materials(170.3880) Medical and biological imaging(180.4315) Nonlinear microscopy(190.4160) Multiharmonic generation(190.4180) Multiphoton processes

Identifiers

PMID28270981
PMCPMC5330564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.