ArticleBiomedical optics express2017
Normalization of compression-induced hemodynamics in patients responding to neoadjuvant chemotherapy monitored by dynamic tomographic optical breast imaging (DTOBI).
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Innovative Discrete Multi-Wavelength Near-Infrared Spectroscopic (DMW-NIRS) Imaging for Rapid Breast Lesion Differentiation: Feasibility Study.Diagnostics (Basel, Switzerland) · 2025Article
- Monte Carlo simulation of spatial frequency domain imaging for breast tumors during compression.Journal of biomedical optics · 2024Article
- Functional hemodynamic imaging markers for the prediction of pathological outcomes in breast cancer patients treated with neoadjuvant chemotherapy.Journal of biomedical optics · 2024Article
- FDU-Net: Deep Learning-Based Three-Dimensional Diffuse Optical Image Reconstruction.IEEE transactions on medical imaging · 2023Article
- Method to improve the localization accuracy and contrast recovery of lesions in separately acquired X-ray and diffuse optical tomographic breast imaging.Biomedical optics express · 2022Article
- Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients.Photoacoustics · 2022Article
- High optode-density wearable diffuse optical probe for monitoring paced breathing hemodynamics in breast tissue.Journal of biomedical optics · 2021Article
- Article
- Mechanical and hemodynamic responses of breast tissue under mammographic-like compression during functional dynamic optical imaging.Biomedical optics express · 2020Article
- Diffuse optical spectroscopic imaging reveals distinct early breast tumor hemodynamic responses to metronomic and maximum tolerated dose regimens.Breast cancer research : BCR · 2020Article
- Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters.Breast cancer research : BCR · 2018Article
- Impact of errors in experimental parameters on reconstructed breast images using diffuse optical tomography.Biomedical optics express · 2018Article
- Performance assessment of diffuse optical spectroscopic imaging instruments in a 2-year multicenter breast cancer trialJournal of biomedical optics · 2017Article
- Optical Mammography in Patients with Breast Cancer Undergoing Neoadjuvant Chemotherapy: Individual Clinical Response Index.Academic radiology · 2017Article
- Longitudinal optical monitoring of blood flow in breast tumors during neoadjuvant chemotherapy.Physics in medicine and biology · 2017Article
- Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis.Journal of biomedical optics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
We characterize novel breast cancer imaging biomarkers for monitoring neoadjuvant chemotherapy (NACT) and predicting outcome. Specifically, we recruited 30 patients for a pilot study in which NACT patients were imaged using dynamic tomographic optical breast imaging (DTOBI) to quantify the hemodynamic changes due to partial mammographic compression. DTOBI scans were obtained pre-treatment (referred to as day 0), as well as 7 and 30 days into therapy on female patients undergoing NACT. We present data for the 13 patients who participated in both day 0 and 7 measurements and had evaluable data, of which 7 also returned for day 30 measurements. We acquired optical images over 2 minutes following 4-8 lbs (18-36 N) of compression. The timecourses of tissue-volume averaged total hemoglobin (HbT), as well as hemoglobin oxygen saturation (SO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.