Evidence map›Paper›PMID 28270856›Full record

ReviewNutrition & metabolism2017

Resistance training to improve type 2 diabetes: working toward a prescription for the future.

Dominik H Pesta, Renata L S Goncalves, Anila K Madiraju, Barbara Strasser, Lauren M Sparks

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrition & metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04222231 (Metabolic Effects of a New Resistance Training in Individuals With Type 2 Diabetes), which is not on this map. Cited by 52 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04222231 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Metabolic Effects of a New Resistance Training in Individuals With Type 2 Diabetes

TypeinterventionalSponsorGerman Diabetes CenterRan2019 to 2024Enrolled24ConditionsType 2 DiabetesArmsBlood-flow restriction resistance training, Classical resistance training
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. Association Between Daily Steps Measured by Accelerometry and Diabetes in ELSA-Brasil Participants.International journal of environmental research and public health · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dominik H PestaDepartment of Sport Science, Medical Section, University of Innsbruck, Fürstenweg 185, Innsbruck, Austria.
Renata L S GoncalvesDepartment of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115 USA.
Anila K MadirajuSalk Institute for Biological Studies, 10010N Torrey Pines Rd, La Jolla, CA 92037 USA.
Barbara Strasser *Biocenter, Medical University Innsbruck, Innrain 80-82, Innsbruck, Austria.
Lauren M Sparks *Translational Research Institute for Metabolism and Diabetes, Florida Hospital, 301 E. Princeton Street, Orlando, FL 32804 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of type 2 diabetes (T2D) is rapidly increasing, and effective strategies to manage and prevent this disease are urgently needed. Resistance training (RT) promotes health benefits through increased skeletal muscle mass and qualitative adaptations, such as enhanced glucose transport and mitochondrial oxidative capacity. In particular, mitochondrial adaptations triggered by RT provide evidence for this type of exercise as a feasible lifestyle recommendation to combat T2D, a disease typically characterized by altered muscle mitochondrial function. Recently, the synergistic and antagonistic effects of combined training and Metformin use have come into question and warrant more in-depth prospective investigations. In the future, clinical intervention studies should elucidate the mechanisms driving RT-mitigated mitochondrial adaptations in muscle and their link to improvements in glycemic control, cholesterol metabolism and other cardiovascular disease risk factors in individuals with T2D.

Indexed as

Mitochondrial functionResistance trainingSkeletal muscleType 2 diabetes

Identifiers

PMID28270856
PMCPMC5335813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.