Evidence map›Paper›PMID 28270657›Full record

ArticleNPJ primary care respiratory medicine2017

The impact of poor asthma control among asthma patients treated with inhaled corticosteroids plus long-acting β

Ian D Pavord, Nicola Mathieson, Anna Scowcroft, Riccardo Pedersini, Gina Isherwood, David Price

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Ian D PavordRespiratory Medicine Unit, Nuffield Department of Medicine, NDM Research Building, Old Road Campus, University of Oxford, Oxford, OX3 7FZ, UK. ian.pavord@ndm.ox.ac.uk.
Nicola MathiesonBoehringer Ingelheim Limited, Ellesfield Avenue, Bracknell, Berkshire, RG12 8YS, UK.
Anna ScowcroftBoehringer Ingelheim Limited, Ellesfield Avenue, Bracknell, Berkshire, RG12 8YS, UK.
Riccardo PedersiniKantar Health, Health Outcomes Practice, 19-31 Church Street, Epsom, Surrey, KT17 4PF, UK.
Gina IsherwoodKantar Health, Health Outcomes Practice, 19-31 Church Street, Epsom, Surrey, KT17 4PF, UK.
David PriceAcademic Primary Care, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.ORCID http://orcid.org/0000-0002-9728-9992
Boehringer Ingelheim (United Kingdom) · GBClínica Diagonal · ESHealth Economics and Outcomes Research (United Kingdom) · GBUniversity of Aberdeen · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are several new treatment options for patients whose asthma remains uncontrolled on free-dose and fixed-dose combinations of inhaled corticosteroids plus long-acting β ASTHMA: DRUG COMBO LEAVES MANY WITH UNCONTROLLED DISEASE: Many people who take inhaled steroids combined with long-acting β2-agonist drugs still have poorly controlled asthma. A team led by Ian Pavord from the University of Oxford, UK, identified 701 people from the 2010-2011 UK National Health and Wellness Surveys who were taking this drug combination for their asthma. The researchers found that nearly two-thirds of these individuals had poorly controlled asthma associated with more visits to the emergency room, worse quality of life (both mentally and physically), impaired productivity and other health problems. The calculated direct and indirect costs per person with poorly controlled asthma were about double that for someone whose asthma was under control. The authors conclude that better treatment and management is needed to reduce costs and address the unmet medical need for people with persistent uncontrolled asthma.

Indexed as

AbsenteeismCost of IllnessEfficiencyHealth Care CostsAdministration, InhalationAdolescentAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAdultAgedAsthmaCross-Sectional StudiesDrug Therapy, CombinationEmergency Service, HospitalFemaleHealth StatusAdrenal Cortex HormonesAdrenergic beta-2 Receptor Agonists

Identifiers

PMID28270657
PMCPMC5434793
OpenAlexW2594813104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.