Evidence map›Paper›PMID 28270579›Full record

ArticlemBio2017

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of

Jeff Quigley, V Keith Hughitt, Carlos A Velikovsky, Roy A Mariuzza, Najib M El-Sayed, Volker Briken

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 1 synthesis or guideline pooled it, 236 citations in OpenAlex.

  1. Mucosal immune response in biology, disease prevention and treatment.Signal transduction and targeted therapy · 2025
    Pooled it
  2. Protein kinase F regulates the virulence ofInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. HowVaccines · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. A Porcine-IsolatedBiology · 2026
    Article
  14. PDIM/PGL-deficientMicrobiology resource announcements · 2026
    Article
  15. Article
  16. Review
  17. Host- and pathogen-related determinants of pulmonaryEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  18. Protein-Mediated Virulence in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  19. Genome-wide transcriptional landscape ofFrontiers in immunology · 2026
    Article
  20. Protein kinase F regulates the virulence ofbioRxiv : the preprint server for biology · 2025
    Article

92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeff QuigleyDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
V Keith HughittDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Carlos A VelikovskyDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Roy A MariuzzaDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Najib M El-SayedDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.ORCID 0000-0001-7970-3312
Volker BrikenDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA vbriken@umd.edu.
University of Maryland, College Park · USAdvanced Bioscience Laboratories (United States) · US

Funding

Training in Host-pathogens interactionsT32AI089621 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI LEE, VINCENT T, MCIVER, KEVIN S. · 2010 to 2025
$2.1M
Training Program in Cell & Molecular BiologyT32GM080201 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI DELWICHE, CHARLES F · 2009 to 2019
$1.6M
Characterization of a novel signal transduction pathway in M. tuberculosisR56AI114269 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI BRIKEN, VOLKER · 2014 to 2014
$573k
NIAID NIH HHS R56 AI114269NIAID NIH HHS T32 AI089621NIGMS NIH HHS T32 GM080201
6 · The paper itself

Abstract

The cell wall of

Indexed as

ExocytosisHost-Pathogen InteractionsAutophagyCell DeathCell LineCell WallGene DeletionGlycolipidsHumansMacrophagesMycobacterium tuberculosisOperonPhagosomesRepressor ProteinsTranscription, GeneticVirulenceGlycolipidsRepressor ProteinsVirulence Factors

Identifiers

PMID28270579
PMCPMC5340868
OpenAlexW2592510217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.