Evidence map›Paper›PMID 28270572›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

CREB Signaling Is Involved in Rett Syndrome Pathogenesis.

Qian Bu, Anxin Wang, Hamdi Hamzah, Alex Waldman, Keer Jiang, Qiping Dong, Ronghui Li, Jason Kim, Daniel Turner, Qiang Chang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Meta-Analysis IdentifiesInternational journal of molecular sciences · 2022
    Pooled it
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  8. Deficiency ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
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  12. Advances in the pathogenesis of Rett syndrome using cell models.Animal models and experimental medicine · 2022
    Review
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Qian BuWaisman Center.ORCID 0000-0001-8629-7279
Anxin WangWaisman Center.
Hamdi HamzahWaisman Center.ORCID 0000-0003-2713-7544
Alex WaldmanWaisman Center.ORCID 0000-0002-2016-6118
Keer JiangWaisman Center.
Qiping DongWaisman Center.ORCID 0000-0003-4668-9264
Ronghui LiWaisman Center.
Jason KimWaisman Center.ORCID 0000-0002-5551-5445
Daniel TurnerWaisman Center.ORCID 0000-0001-8159-2594
Qiang ChangWaisman Center, qchang@waisman.wisc.edu.ORCID 0000-0002-7625-2170
Pisgah Astronomical Research Institute · USUniversity of Wisconsin–Madison · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2016 to 2020
$6.0M
NICHD NIH HHS P30 HD003352NICHD NIH HHS U54 HD090256
6 · The paper itself

Abstract

Rett syndrome (RTT) is a debilitating neurodevelopmental disorder caused by mutations in the

Indexed as

AnimalsCell LineCREB-Binding ProteinDisease ProgressionFemaleHumansMiceMice, Inbred C57BLMice, KnockoutNeural Stem CellsRett SyndromeSignal TransductionCREB-Binding ProteinCREBBP protein, humanCrebbp protein, mouseCREBhESCiPSCMECP2Rett syndromerolipram

Identifiers

PMID28270572
PMCPMC5373141
OpenAlexW2593918913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.