Evidence map›Paper›PMID 28269830›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2016

An Extended SNOMED CT Concept Model for Observations in Molecular Genetics.

James R Campbell, Geoffrey Talmon, Allison Cushman-Vokoun, Daniel Karlsson, W Scott Campbell

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Structured Data Capture for Oncology.JCO clinical cancer informatics · 2021
    Article
  3. Article
  4. Genomics and electronic health record systems.Human molecular genetics · 2018
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James R CampbellUniversity of Nebraska Medical Center, Omaha NE USA.
Geoffrey TalmonUniversity of Nebraska Medical Center, Omaha NE USA.
Allison Cushman-VokounUniversity of Nebraska Medical Center, Omaha NE USA.
Daniel KarlssonDepartment of Biomedical Engineering, Linköping University; Linköping, Sweden.
W Scott CampbellUniversity of Nebraska Medical Center, Omaha NE USA.

Funding

Deploying ONC national Standards in Support of Metadata for Big Data Research Warehouse Management of Repurposed Laboratory, Pathology & Patient Findings Data From the EHR.U01HG009455 · NHGRI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CAMPBELL, WALTER SCOTT · 2016 to 2018
$1.7M
NHGRI NIH HHS U01 HG009455
6 · The paper itself

Abstract

Molecular genetics laboratory reports are multiplying and increasingly of clinical importance in diagnosis and treatment of cancer, infectious disease and managing of public health. Little of this data is structured or maintained in the EHR in format useful for decision support or research. Structured, computable reporting is limited by non-availability of a domain ontology for these data. The IHTSDO and Regenstrief Institute(RI) have been collaborating since 2008 to develop a unified concept model and ontology of observable entities - concepts which represent the results of laboratory and clinical observations. In this paper we report the progress we have made to apply that unified concept model to the structured recording of observations in clinical molecular genetic pathology including immunohistochemistry and sequence variant findings. The primary use case for deployment is the structured and coded reporting of Cancer checklist

Indexed as

Gene OntologyMolecular BiologySystematized Nomenclature of MedicineBiomarkers, TumorHumansLogical Observation Identifiers Names and CodesModels, TheoreticalBiomarkers, Tumor

Identifiers

PMID28269830
PMCPMC5333284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.